Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3SBR

Pseudomonas stutzeri nitrous oxide reductase, P1 crystal form with substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004129	molecular_function	cytochrome-c oxidase activity
A	0005507	molecular_function	copper ion binding
A	0005509	molecular_function	calcium ion binding
A	0016020	cellular_component	membrane
A	0050304	molecular_function	nitrous-oxide reductase activity
B	0004129	molecular_function	cytochrome-c oxidase activity
B	0005507	molecular_function	copper ion binding
B	0005509	molecular_function	calcium ion binding
B	0016020	cellular_component	membrane
B	0050304	molecular_function	nitrous-oxide reductase activity
C	0004129	molecular_function	cytochrome-c oxidase activity
C	0005507	molecular_function	copper ion binding
C	0005509	molecular_function	calcium ion binding
C	0016020	cellular_component	membrane
C	0050304	molecular_function	nitrous-oxide reductase activity
D	0004129	molecular_function	cytochrome-c oxidase activity
D	0005507	molecular_function	copper ion binding
D	0005509	molecular_function	calcium ion binding
D	0016020	cellular_component	membrane
D	0050304	molecular_function	nitrous-oxide reductase activity
E	0004129	molecular_function	cytochrome-c oxidase activity
E	0005507	molecular_function	copper ion binding
E	0005509	molecular_function	calcium ion binding
E	0016020	cellular_component	membrane
E	0050304	molecular_function	nitrous-oxide reductase activity
F	0004129	molecular_function	cytochrome-c oxidase activity
F	0005507	molecular_function	copper ion binding
F	0005509	molecular_function	calcium ion binding
F	0016020	cellular_component	membrane
F	0050304	molecular_function	nitrous-oxide reductase activity
G	0004129	molecular_function	cytochrome-c oxidase activity
G	0005507	molecular_function	copper ion binding
G	0005509	molecular_function	calcium ion binding
G	0016020	cellular_component	membrane
G	0050304	molecular_function	nitrous-oxide reductase activity
H	0004129	molecular_function	cytochrome-c oxidase activity
H	0005507	molecular_function	copper ion binding
H	0005509	molecular_function	calcium ion binding
H	0016020	cellular_component	membrane
H	0050304	molecular_function	nitrous-oxide reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA A 701

Chain	Residue
A	HIS583
A	CYS618
A	TRP620
A	CYS622
A	HIS626
A	MET629

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE CUK A 702

Chain	Residue
A	HIS326
A	HIS382
A	HIS433
A	LYS454
A	HIS494
B	PHE621
A	HIS129
A	HIS130
A	HIS178

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 703

Chain	Residue
A	TYR256
A	GLU259
A	MET267
A	ASP273
A	ASN324

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 704

Chain	Residue
A	ARG181
A	ASN241
A	GLY327
A	CYS328
A	ASN329
A	HIS382

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K A 705

Chain	Residue
A	LYS454
A	GLU469
A	HOH2625
B	HOH2626

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA B 701

Chain	Residue
B	HIS583
B	CYS618
B	TRP620
B	CYS622
B	HIS626
B	MET629

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CUK B 702

Chain	Residue
B	HIS129
B	HIS130
B	HIS178
B	HIS326
B	HIS382
B	HIS433
B	HIS494

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 703

Chain	Residue
B	TYR256
B	GLU259
B	MET267
B	ASP273
B	ASN324
B	HOH2592

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL B 704

Chain	Residue
B	ARG181
B	ASN241
B	CYS328
B	ASN329
B	HIS382

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K B 705

Chain	Residue
A	ASP580
B	LYS454
B	GLU469
B	HOH2245
B	HOH2508

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA C 701

Chain	Residue
C	HIS583
C	CYS618
C	TRP620
C	CYS622
C	HIS626
C	MET629

site_id	BC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CUK C 702

Chain	Residue
C	HIS129
C	HIS130
C	HIS178
C	ASN241
C	HIS326
C	HIS382
C	HIS433
C	HIS494
D	PHE621
D	N2O640

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 703

Chain	Residue
C	TYR256
C	GLU259
C	MET267
C	ASP273
C	ASN324
C	HOH2673

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL C 704

Chain	Residue
C	ARG181
C	ASN241
C	GLY327
C	CYS328
C	ASN329
C	HIS382

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K C 705

Chain	Residue
C	LYS454
C	GLU469
C	HOH738
C	HOH2690

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA D 701

Chain	Residue
D	HIS583
D	CYS618
D	TRP620
D	CYS622
D	HIS626
D	MET629

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CUK D 702

Chain	Residue
D	HIS130
D	HIS178
D	HIS326
D	HIS382
D	HIS433
D	HIS494
C	PHE621
D	HIS129

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 703

Chain	Residue
D	TYR256
D	GLU259
D	MET267
D	ASP273
D	ASN324
D	HOH2725

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL D 704

Chain	Residue
D	ARG181
D	ASN241
D	GLY327
D	CYS328
D	ASN329
D	HIS382

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K D 705

Chain	Residue
C	HOH1305
C	HOH1306
C	HOH2256
D	LYS454
D	GLU469
D	HOH1307

site_id	CC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE IMD D 639

Chain	Residue
C	TRP615
C	HOH1386
D	GLU196
D	PHE197
D	ILE198
D	ASN238
D	TYR256
D	ASN257
D	MET267

site_id	CC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE N2O D 640

Chain	Residue
C	HIS129
C	HIS494
C	CUK702
D	PHE621
D	HIS626
D	MET627
D	HOH653

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA E 701

Chain	Residue
E	HIS583
E	CYS618
E	TRP620
E	CYS622
E	HIS626
E	MET629

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CUK E 702

Chain	Residue
E	HIS129
E	HIS130
E	HIS178
E	ASN241
E	HIS326
E	HIS382
E	HIS433
E	HIS494

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA E 703

Chain	Residue
E	TYR256
E	GLU259
E	MET267
E	ASP273
E	ASN324

site_id	CC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL E 704

Chain	Residue
E	ARG181
E	GLY327
E	CYS328
E	ASN329
E	HIS382

site_id	CC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K E 705

Chain	Residue
E	LYS454
E	GLU469
E	HOH1296
F	ASP580
F	HOH1295

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IMD E 639

Chain	Residue
E	GLY541
E	LYS563
E	ASP566

site_id	DC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE IMD E 640

Chain	Residue
E	GLU196
E	PHE197
E	ILE198
E	ASN238
E	TYR256
E	ASN257
E	MET267
E	HOH1298
F	TRP615

site_id	DC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA F 701

Chain	Residue
F	HIS583
F	CYS618
F	TRP620
F	CYS622
F	HIS626
F	MET629

site_id	DC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CUK F 702

Chain	Residue
E	PHE621
F	HIS129
F	HIS130
F	HIS178
F	HIS326
F	HIS382
F	HIS433
F	HIS494

site_id	DC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA F 703

Chain	Residue
F	TYR256
F	GLU259
F	MET267
F	ASP273
F	ASN324
F	HOH2077

site_id	DC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL F 704

Chain	Residue
F	ARG181
F	ASN241
F	CYS328
F	ASN329
F	HIS382

site_id	DC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K F 705

Chain	Residue
E	HOH1289
F	LYS454
F	GLU469
F	HOH1288
F	HOH2065
F	HOH2594

site_id	DC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IMD F 639

Chain	Residue
E	TRP615
F	PHE197
F	ILE198
F	ASN238
F	ASN257

site_id	DC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA G 701

Chain	Residue
G	HIS583
G	CYS618
G	TRP620
G	CYS622
G	HIS626
G	MET629

site_id	EC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE CUK G 702

Chain	Residue
G	HIS129
G	HIS130
G	HIS178
G	HIS326
G	HIS382
G	HIS433
G	HIS494
H	PHE621
H	N2O640

site_id	EC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA G 703

Chain	Residue
G	TYR256
G	GLU259
G	MET267
G	ASP273
G	ASN324

site_id	EC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL G 704

Chain	Residue
G	ARG181
G	ASN241
G	CYS328
G	ASN329
G	HIS382

site_id	EC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE K G 705

Chain	Residue
G	LYS454
G	GLU469
G	HOH688
G	HOH1308
H	HOH733

site_id	EC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IMD G 639

Chain	Residue
G	GLU196
G	PHE197
G	ILE198
G	ASN238
G	TYR256
G	ASN257
G	MET267
H	TRP615

site_id	EC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CUA H 701

Chain	Residue
H	HIS583
H	CYS618
H	TRP620
H	CYS622
H	HIS626
H	MET629

site_id	EC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CUK H 702

Chain	Residue
H	HIS129
H	HIS130
H	HIS178
H	ASN241
H	HIS326
H	HIS382
H	HIS433
H	HIS494

site_id	EC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA H 703

Chain	Residue
H	TYR256
H	GLU259
H	MET267
H	ASP273
H	ASN324

site_id	EC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL H 704

Chain	Residue
H	ARG181
H	ASN241
H	GLY327
H	CYS328
H	ASN329
H	HIS382

site_id	FC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K H 705

Chain	Residue
G	ASP580
G	HOH2946
H	LYS454
H	GLU469
H	HOH712
H	HOH2251

site_id	FC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE IMD H 639

Chain	Residue
G	TRP615
H	GLU196
H	PHE197
H	ILE198
H	ASN238
H	TYR256
H	ASN257
H	MET267
H	HOH686

site_id	FC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE N2O H 640

Chain	Residue
G	HIS129
G	HIS494
G	CUK702
G	HOH2138
H	PHE621
H	HIS626
H	MET627

Functional Information from PROSITE/UniProt

site_id	PS00078
Number of Residues	49
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. VsHgfvvvnhgvsmeispqqtssitfvadkpglhwyy......CswfChalHmeM

Chain	Residue	Details
A	VAL581-MET629

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	768
Details	Region: {"description":"COX2-like"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	160
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)