Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3SA9

Crystal structure of Wild-type HIV-1 protease in complex With AF68

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0016787molecular_functionhydrolase activity
A0055036cellular_componentvirion membrane
A0072494cellular_componenthost multivesicular body
B0004190molecular_functionaspartic-type endopeptidase activity
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0016787molecular_functionhydrolase activity
B0055036cellular_componentvirion membrane
B0072494cellular_componenthost multivesicular body
Functional Information from PDB Data
site_idAC1
Number of Residues19
DetailsBINDING SITE FOR RESIDUE A68 A 200
ChainResidue
AASP25
AHOH109
BASP25
BGLY27
BALA28
BASP30
BGLY48
BGLY49
BILE50
BPRO81
BILE84
AGLY27
AALA28
AASP29
AASP30
AGLY48
AGLY49
AILE50
AHOH108

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE PO4 A 100
ChainResidue
AARG14
AGLY16
AGLY17
BGLY16
BHOH144

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ACT A 101
ChainResidue
APRO1
AHIS69
AHOH117
AHOH168
AHOH169

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL
ChainResidueDetails
AALA22-LEU33

246333

PDB entries from 2025-12-17

PDB statisticsPDBj update infoContact PDBjnumon