3S9F
The structure of Tryparedoxin I from Leishmania major
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0030178 | biological_process | negative regulation of Wnt signaling pathway |
| A | 0031397 | biological_process | negative regulation of protein ubiquitination |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 146 |
| Chain | Residue |
| A | LEU112 |
| A | THR125 |
| A | ARG126 |
| A | ALA127 |
| A | ARG128 |
| A | HOH180 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 147 |
| Chain | Residue |
| A | HOH158 |
| A | HOH159 |
| A | ARG15 |
| A | PRO90 |
| A | PHE91 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 148 |
| Chain | Residue |
| A | ASN93 |
| A | ASN93 |
| A | ASN95 |
| A | ILE96 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 149 |
| Chain | Residue |
| A | HIS7 |
| A | GLU10 |
| A | ALA11 |
| A | HOH178 |
| A | HOH187 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 150 |
| Chain | Residue |
| A | HIS58 |
| A | HOH169 |
| A | HOH170 |
| A | HOH171 |
| A | HOH172 |
| A | HOH175 |
| A | HOH176 |
