Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004478 | molecular_function | methionine adenosyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006556 | biological_process | S-adenosylmethionine biosynthetic process |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004478 | molecular_function | methionine adenosyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006556 | biological_process | S-adenosylmethionine biosynthetic process |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 404 |
| Chain | Residue |
| A | ALA309 |
| A | LYS400 |
| A | HOH509 |
| A | HOH969 |
| B | ASN225 |
| B | ASN229 |
| B | HOH467 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | HOH1651 |
| A | HOH1792 |
| B | GLU187 |
| B | GLU189 |
| A | ASP234 |
| A | HOH1647 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CA A 405 |
| Chain | Residue |
| A | ASN394 |
| A | ASP397 |
| A | ASP398 |
| A | HOH696 |
| A | HOH741 |
| A | HOH848 |
| A | HOH1140 |
| B | HOH463 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 405 |
| Chain | Residue |
| A | HOH1659 |
| B | ASN394 |
| B | ASP397 |
| B | ASP398 |
| B | HOH1744 |
| B | HOH1773 |
| B | HOH1774 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 406 |
| Chain | Residue |
| A | ARG401 |
| B | ARG401 |
| B | HOH1803 |
| B | HOH1804 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 408 |
| Chain | Residue |
| A | PHE188 |
| A | ASP191 |
| A | ARG314 |
| A | HOH477 |
| B | HOH1666 |
Functional Information from PROSITE/UniProt
| site_id | PS00376 |
| Number of Residues | 11 |
| Details | ADOMET_SYNTHASE_1 S-adenosylmethionine synthase signature 1. GAGDQGlmfGY |
| Chain | Residue | Details |
| A | GLY131-TYR141 | |
| site_id | PS00377 |
| Number of Residues | 9 |
| Details | ADOMET_SYNTHASE_2 S-adenosylmethionine synthase signature 2. GGGAFSgKD |
| Chain | Residue | Details |
| A | GLY279-ASP287 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS17 | |
| B | GLN104 | |
| B | ASP179 | |
| B | LYS250 | |
| B | ARG265 | |
| B | LYS290 | |
| A | GLU58 | |
| A | GLN104 | |
| A | ASP179 | |
| A | LYS250 | |
| A | ARG265 | |
| A | LYS290 | |
| B | HIS17 | |
| B | GLU58 | |
| Chain | Residue | Details |
| A | ASP19 | |
| B | LYS286 | |
| A | GLU45 | |
| A | ASP259 | |
| A | ALA282 | |
| A | LYS286 | |
| B | ASP19 | |
| B | GLU45 | |
| B | ASP259 | |
| B | ALA282 | |
