3S6I

Schizosaccaromyces pombe 3-methyladenine DNA glycosylase (Mag1) in complex with abasic-DNA.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0003824	molecular_function	catalytic activity
A	0003905	molecular_function	alkylbase DNA N-glycosylase activity
A	0005634	cellular_component	nucleus
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0006285	biological_process	base-excision repair, AP site formation
A	0006307	biological_process	DNA alkylation repair
A	0008725	molecular_function	DNA-3-methyladenine glycosylase activity
A	0032131	molecular_function	alkylated DNA binding
A	0043916	molecular_function	DNA-7-methylguanine glycosylase activity
A	0052820	molecular_function	DNA-1,N6-ethenoadenine N-glycosylase activity
D	0003684	molecular_function	damaged DNA binding
D	0003824	molecular_function	catalytic activity
D	0003905	molecular_function	alkylbase DNA N-glycosylase activity
D	0005634	cellular_component	nucleus
D	0006281	biological_process	DNA repair
D	0006284	biological_process	base-excision repair
D	0006285	biological_process	base-excision repair, AP site formation
D	0006307	biological_process	DNA alkylation repair
D	0008725	molecular_function	DNA-3-methyladenine glycosylase activity
D	0032131	molecular_function	alkylated DNA binding
D	0043916	molecular_function	DNA-7-methylguanine glycosylase activity
D	0052820	molecular_function	DNA-1,N6-ethenoadenine N-glycosylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 229

Chain	Residue
A	THR142
A	ILE144
A	ILE147
B	DC10
B	HOH15
B	HOH39

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA D 229

Chain	Residue
D	HOH251
E	DC10
E	HOH38
D	THR142
D	ILE144
D	ILE147

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Functional Information from PROSITE/UniProt

site_id	PS00516
Number of Residues	25
Details	ALKYLBASE_DNA_GLYCOS Alkylbase DNA glycosidases alkA family signature. GIGrWTVeMLlIfslnrddvMpaDD

Chain	Residue	Details
A	GLY146-ASP170

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Site: {"description":"Determinant for substrate specificity and/or activity","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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