3S5H
Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005774 | cellular_component | vacuolar membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0020011 | cellular_component | apicoplast |
| A | 0020020 | cellular_component | food vacuole |
| A | 0031982 | cellular_component | vesicle |
| A | 0042540 | biological_process | hemoglobin catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051603 | biological_process | proteolysis involved in protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CO A 1195 |
| Chain | Residue |
| A | HIS129 |
| A | HIS133 |
| A | GLU243 |
| A | HOH1320 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10096","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2011","submissionDatabase":"PDB data bank","title":"Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum.","authors":["Morgunova E.","Ponpuak M.","Istvan E.","Popov A.","Goldberg D.","Eneqvist T."]}},{"source":"PDB","id":"3S5K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3S5M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
