Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3S56

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug saquinavir

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0016787molecular_functionhydrolase activity
A0042802molecular_functionidentical protein binding
A0044174cellular_componenthost cell endosome
A0055036cellular_componentvirion membrane
A0072494cellular_componenthost multivesicular body
B0004190molecular_functionaspartic-type endopeptidase activity
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0016787molecular_functionhydrolase activity
B0042802molecular_functionidentical protein binding
B0044174cellular_componenthost cell endosome
B0055036cellular_componentvirion membrane
B0072494cellular_componenthost multivesicular body
Functional Information from PDB Data
site_idAC1
Number of Residues19
DetailsBINDING SITE FOR RESIDUE ROC A 201
ChainResidue
AASP25
ATHR80
APRO81
AILE82
BARG8
BLEU23
BASP25
BGLY27
BGLY48
BILE50
BILE84
AGLY27
AALA28
AASP29
AASP30
AGLY48
AGLY49
AILE50
ALYS55

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE ROC B 203
ChainResidue
AARG8
APRO44
APRO81
AROC201
BARG8
BGLU21
BGLU34
BPRO81
BILE82

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ACT B 501
ChainResidue
AROC201
BGLY27
BASP29
BHOH1030

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTII
ChainResidueDetails
AALA22-ILE33

239492

PDB entries from 2025-07-30

PDB statisticsPDBj update infoContact PDBjnumon