3S4W
Structure of the FANCI-FANCD2 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0031398 | biological_process | positive regulation of protein ubiquitination |
| A | 0043240 | cellular_component | Fanconi anaemia nuclear complex |
| A | 0070182 | molecular_function | DNA polymerase binding |
| A | 1990391 | cellular_component | DNA repair complex |
| B | 0000793 | cellular_component | condensed chromosome |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005730 | cellular_component | nucleolus |
| B | 0005829 | cellular_component | cytosol |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0007129 | biological_process | homologous chromosome pairing at meiosis |
| B | 0007276 | biological_process | gamete generation |
| B | 0010332 | biological_process | response to gamma radiation |
| B | 0016604 | cellular_component | nuclear body |
| B | 0031573 | biological_process | mitotic intra-S DNA damage checkpoint signaling |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0036297 | biological_process | interstrand cross-link repair |
| B | 0045589 | biological_process | regulation of regulatory T cell differentiation |
| B | 0048854 | biological_process | brain morphogenesis |
| B | 0050727 | biological_process | regulation of inflammatory response |
| B | 0070182 | molecular_function | DNA polymerase binding |
| B | 0097150 | biological_process | neuronal stem cell population maintenance |
| B | 1990391 | cellular_component | DNA repair complex |
| B | 1990918 | biological_process | double-strand break repair involved in meiotic recombination |
| B | 2000348 | biological_process | regulation of CD40 signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17412408","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17412408","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9NVI1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9NVI1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q9NVI1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9BXW9","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q9BXW9","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
