3S1W

Transaldolase variant Lys86Ala from Thermoplasma acidophilum in complex with glycerol and citrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004801	molecular_function	transaldolase activity
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0016740	molecular_function	transferase activity
A	0016832	molecular_function	aldehyde-lyase activity
B	0004801	molecular_function	transaldolase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0016740	molecular_function	transferase activity
B	0016832	molecular_function	aldehyde-lyase activity
C	0004801	molecular_function	transaldolase activity
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0016740	molecular_function	transferase activity
C	0016832	molecular_function	aldehyde-lyase activity
D	0004801	molecular_function	transaldolase activity
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0016740	molecular_function	transferase activity
D	0016832	molecular_function	aldehyde-lyase activity
E	0004801	molecular_function	transaldolase activity
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0006098	biological_process	pentose-phosphate shunt
E	0016740	molecular_function	transferase activity
E	0016832	molecular_function	aldehyde-lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GOL A 224

Chain	Residue
A	ASP6
A	FLC225
A	HOH662
A	HOH843
A	THR26
A	THR27
A	ASN28
A	ASN108
A	THR110
A	SER130
A	PHE132
A	LEU164

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC A 225

Chain	Residue
A	ASP6
A	PHE132
A	ARG135
A	SER167
A	ARG169
A	GOL224
A	HOH390
A	HOH451
A	HOH837
A	HOH838

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL B 224

Chain	Residue
B	ASP6
B	THR26
B	THR27
B	ASN28
B	ASN108
B	THR110
B	SER130
B	PHE132
B	FLC225
B	HOH429
B	HOH609

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC B 225

Chain	Residue
B	ASP6
B	PHE132
B	ARG135
B	SER167
B	ARG169
B	GOL224
B	HOH238
B	HOH278
B	HOH283
B	HOH383

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL C 224

Chain	Residue
C	ASP6
C	THR26
C	THR27
C	ASN28
C	ASN108
C	THR110
C	SER130
C	PHE132
C	FLC225
C	HOH824
C	HOH839

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC C 225

Chain	Residue
C	ASP6
C	PHE132
C	ARG135
C	SER167
C	ARG169
C	GOL224
C	HOH257
C	HOH274
C	HOH825
C	HOH827

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL D 224

Chain	Residue
D	ASP6
D	THR26
D	THR27
D	ASN28
D	ASN108
D	THR110
D	SER130
D	PHE132
D	FLC225
D	HOH616

---

site_id	AC8
Number of Residues	11
Details	BINDING SITE FOR RESIDUE FLC D 225

Chain	Residue
D	ASP6
D	PHE132
D	ARG135
D	SER167
D	ARG169
D	GOL224
D	HOH232
D	HOH392
D	HOH617
D	HOH619
D	HOH620

---

site_id	AC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL E 224

Chain	Residue
E	ASP6
E	THR26
E	THR27
E	ASN28
E	ASN108
E	SER130
E	PHE132
E	ALA166
E	FLC225

---

site_id	BC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC E 225

Chain	Residue
E	GOL224
E	HOH830
E	HOH833
E	HOH836
E	HOH840
E	ASP6
E	PHE132
E	ARG135
E	SER167
E	ARG169

---

Functional Information from PROSITE/UniProt

site_id	PS01054
Number of Residues	9
Details	TRANSALDOLASE_1 Transaldolase signature 1. GVTTNPTLI

Chain	Residue	Details
A	GLY24-ILE32

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000250

Chain	Residue	Details
A	ALA86
B	ALA86
C	ALA86
D	ALA86
E	ALA86

---