3RWG
Rhesus macaque MHC class I molecule Mamu-B*17-MW9
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0002474 | biological_process | antigen processing and presentation of peptide antigen via MHC class I |
| B | 0002503 | biological_process | peptide antigen assembly with MHC class II protein complex |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005765 | cellular_component | lysosomal membrane |
| B | 0006955 | biological_process | immune response |
| B | 0019886 | biological_process | antigen processing and presentation of exogenous peptide antigen via MHC class II |
| B | 0023026 | molecular_function | MHC class II protein complex binding |
| B | 0031902 | cellular_component | late endosome membrane |
| B | 0042605 | molecular_function | peptide antigen binding |
| B | 0042612 | cellular_component | MHC class I protein complex |
| B | 0042613 | cellular_component | MHC class II protein complex |
| B | 0050778 | biological_process | positive regulation of immune response |
| B | 0050870 | biological_process | positive regulation of T cell activation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE XPE A 277 |
| Chain | Residue |
| A | GLU58 |
| A | NA278 |
| A | ARG66 |
| A | TYR84 |
| A | TYR85 |
| A | ASN86 |
| A | ASP137 |
| A | GLU166 |
| A | TRP167 |
| A | ARG170 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 278 |
| Chain | Residue |
| A | XPE277 |
| A | HOH320 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 100 |
| Chain | Residue |
| B | ASP34 |
| B | ILE35 |
| B | HOH247 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG B 101 |
| Chain | Residue |
| A | GLU229 |
| A | VAL231 |
| A | ARG234 |
| A | TRP244 |
| B | GLN8 |
| B | VAL9 |
| B | MET99 |
| B | HOH174 |
| B | HOH209 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH |
| Chain | Residue | Details |
| B | TYR78-HIS84 | |
| A | TYR257-HIS263 |
