Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003724 | molecular_function | RNA helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| B | 0005643 | cellular_component | nuclear pore |
| B | 0016973 | biological_process | poly(A)+ mRNA export from nucleus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP A 1 |
| Chain | Residue |
| A | PHE112 |
| A | LYS144 |
| A | THR145 |
| A | ALA146 |
| A | ASP395 |
| A | PHE430 |
| A | LYS114 |
| A | SER116 |
| A | GLN119 |
| A | GLN139 |
| A | SER140 |
| A | GLY141 |
| A | THR142 |
| A | GLY143 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE IHP B 1 |
| Chain | Residue |
| A | LYS477 |
| A | LYS481 |
| B | MG2 |
| B | LYS264 |
| B | LYS333 |
| B | ARG337 |
| B | ARG374 |
| B | LYS377 |
| B | LYS378 |
| B | LYS401 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG B 2 |
Functional Information from PROSITE/UniProt
| site_id | PS00039 |
| Number of Residues | 9 |
| Details | DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADNmL |
| Chain | Residue | Details |
| A | VAL237-LEU245 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 167 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"DEAD box"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 281 |
| Details | Region: {"description":"Interactions with NUP42, DBP5 and GFD1"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | Motif: {"description":"Bipartite nuclear localization signal 2"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Repeat: {"description":"FG 1"} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Repeat: {"description":"PXFG 1"} |
