Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3RQU

Crystal structure of a prokaryotic pentameric ligand-gated ion channel, ELIC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0007165	biological_process	signal transduction
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042391	biological_process	regulation of membrane potential
A	0042802	molecular_function	identical protein binding
A	0043005	cellular_component	neuron projection
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0007165	biological_process	signal transduction
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042391	biological_process	regulation of membrane potential
B	0042802	molecular_function	identical protein binding
B	0043005	cellular_component	neuron projection
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0007165	biological_process	signal transduction
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042391	biological_process	regulation of membrane potential
C	0042802	molecular_function	identical protein binding
C	0043005	cellular_component	neuron projection
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0007165	biological_process	signal transduction
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042391	biological_process	regulation of membrane potential
D	0042802	molecular_function	identical protein binding
D	0043005	cellular_component	neuron projection
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0007165	biological_process	signal transduction
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042391	biological_process	regulation of membrane potential
E	0042802	molecular_function	identical protein binding
E	0043005	cellular_component	neuron projection
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0007165	biological_process	signal transduction
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042391	biological_process	regulation of membrane potential
F	0042802	molecular_function	identical protein binding
F	0043005	cellular_component	neuron projection
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0007165	biological_process	signal transduction
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042391	biological_process	regulation of membrane potential
G	0042802	molecular_function	identical protein binding
G	0043005	cellular_component	neuron projection
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0007165	biological_process	signal transduction
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0042391	biological_process	regulation of membrane potential
H	0042802	molecular_function	identical protein binding
H	0043005	cellular_component	neuron projection
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0007165	biological_process	signal transduction
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
I	0042391	biological_process	regulation of membrane potential
I	0042802	molecular_function	identical protein binding
I	0043005	cellular_component	neuron projection
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0007165	biological_process	signal transduction
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
J	0042391	biological_process	regulation of membrane potential
J	0042802	molecular_function	identical protein binding
J	0043005	cellular_component	neuron projection

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MES A 323

Chain	Residue
A	TRP206
B	THR259
B	GLN264

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 324

Chain	Residue
A	PRO11
A	ASN136
A	ASN137
A	GLN138
A	HOH327

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MES B 323

Chain	Residue
C	THR259
C	GLN264
B	TRP206

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 324

Chain	Residue
B	ASN60
C	PRO74
C	ALA75
C	TYR102

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 325

Chain	Residue
B	ASN251
C	ASN251
D	ASN251
E	ASN251

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL B 326

Chain	Residue
B	GLY88
B	ASN89
C	SER84

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 327

Chain	Residue
A	GLU59
A	ASN60
B	VAL73
B	TYR102

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 328

Chain	Residue
B	PRO11
B	ASN136
B	ASN137
B	GLN138
B	GLU187
B	HOH330

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MES C 323

Chain	Residue
C	TRP206
D	THR259
D	GLN264

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 324

Chain	Residue
C	ASN136
C	ASN137
C	GLU187
C	HOH325

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MES D 323

Chain	Residue
D	TRP206
D	HOH332
E	GLN264

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 324

Chain	Residue
D	PRO74
D	ALA75
D	LYS90
D	TYR102

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL D 325

Chain	Residue
D	VAL82
D	SER109

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D 326

Chain	Residue
D	PRO11
D	ASN136
D	ASN137
D	GLN138
D	HOH329

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL E 323

Chain	Residue
A	GLN264
E	TRP206

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 324

Chain	Residue
E	PRO11
E	ASN136
E	ASN137
E	GLN138
E	GLU187
E	HOH325

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 323

Chain	Residue
F	PRO11
F	ASN136
F	ASN137
F	GLN138
F	HOH324

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MES G 323

Chain	Residue
F	TRP206
G	THR259
G	GLN264

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MES G 324

Chain	Residue
G	TRP206
H	THR259
H	GLN264

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL G 325

Chain	Residue
G	PRO11
G	ASN136
G	ASN137
G	GLN138
G	HOH328

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 323

Chain	Residue
H	PRO11
H	ASN136
H	ASN137
H	GLN138
H	HOH326

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MES I 323

Chain	Residue
I	TRP206
J	GLN264

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL I 324

Chain	Residue
I	GLN264

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL I 325

Chain	Residue
H	ASN60
I	VAL73
I	PRO74
I	ALA75
I	TYR102

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL I 326

Chain	Residue
I	PRO11
I	ASN136
I	ASN137
I	GLU187
I	HOH328

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL J 323

Chain	Residue
F	GLN264
J	TRP206

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL J 324

Chain	Residue
J	TYR102
I	ASN60
J	LYS90

site_id	DC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL J 325

Chain	Residue
J	PRO11
J	ASN136
J	ASN137
J	GLN138
J	HOH327

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)