3RQH

Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis in complex with P1,P6-Di(adenosine-5') hexaphosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016829	molecular_function	lyase activity
A	0016836	molecular_function	hydro-lyase activity
A	0046496	biological_process	nicotinamide nucleotide metabolic process
A	0052855	molecular_function	ADP-dependent NAD(P)H-hydrate dehydratase activity
A	0052856	molecular_function	NADHX epimerase activity
A	0052857	molecular_function	NADPHX epimerase activity
A	0110051	biological_process	metabolite repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 277

Chain	Residue
A	LYS186
A	B6P278
A	HOH309
A	HOH314

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site_id	AC2
Number of Residues	28
Details	BINDING SITE FOR RESIDUE B6P A 278

Chain	Residue
A	LYS186
A	GLY187
A	THR190
A	ASN206
A	GLY207
A	LEU209
A	ALA210
A	GLY212
A	GLY213
A	THR214
A	GLY215
A	ASP216
A	LEU218
A	HIS243
A	MG277
A	HOH300
A	HOH309
A	HOH314
A	HOH328
A	HOH336
A	HOH352
A	HOH380
A	HOH392
A	ALA20
A	SER22
A	LYS24
A	LYS57
A	HIS149

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE B6P A 279

Chain	Residue
A	TYR79
A	TRP80
A	GLN91
A	LEU92
A	GLU93
A	GLU94
A	TYR96
A	HOH393

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Functional Information from PROSITE/UniProt

site_id	PS01049
Number of Residues	11
Details	YJEF_C_1 YjeF C-terminal domain signature 1. AIAIGPGLPqT

Chain	Residue	Details
A	ALA98-THR108

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site_id	PS01050
Number of Residues	11
Details	YJEF_C_2 YjeF C-terminal domain signature 2. GGtGDTLTGmI

Chain	Residue	Details
A	GLY212-ILE222

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:22940582, ECO:0007744|PDB:3RPZ

Chain	Residue	Details
A	ALA42
A	GLY104
A	HIS149
A	LYS186
A	GLY215
A	ASP216

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