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3RPP

Crystal structure of human kappa class glutathione transferase in apo form

Functional Information from GO Data
ChainGOidnamespacecontents
A0004364molecular_functionglutathione transferase activity
A0004602molecular_functionglutathione peroxidase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005759cellular_componentmitochondrial matrix
A0005777cellular_componentperoxisome
A0005782cellular_componentperoxisomal matrix
A0005829cellular_componentcytosol
A0006749biological_processglutathione metabolic process
A0016020cellular_componentmembrane
A0016491molecular_functionoxidoreductase activity
A0016740molecular_functiontransferase activity
A0030855biological_processepithelial cell differentiation
A0043231cellular_componentintracellular membrane-bounded organelle
A0070062cellular_componentextracellular exosome
A0098869biological_processcellular oxidant detoxification
B0004364molecular_functionglutathione transferase activity
B0004602molecular_functionglutathione peroxidase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005759cellular_componentmitochondrial matrix
B0005777cellular_componentperoxisome
B0005782cellular_componentperoxisomal matrix
B0005829cellular_componentcytosol
B0006749biological_processglutathione metabolic process
B0016020cellular_componentmembrane
B0016491molecular_functionoxidoreductase activity
B0016740molecular_functiontransferase activity
B0030855biological_processepithelial cell differentiation
B0043231cellular_componentintracellular membrane-bounded organelle
B0070062cellular_componentextracellular exosome
B0098869biological_processcellular oxidant detoxification
C0004364molecular_functionglutathione transferase activity
C0004602molecular_functionglutathione peroxidase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005759cellular_componentmitochondrial matrix
C0005777cellular_componentperoxisome
C0005782cellular_componentperoxisomal matrix
C0005829cellular_componentcytosol
C0006749biological_processglutathione metabolic process
C0016020cellular_componentmembrane
C0016491molecular_functionoxidoreductase activity
C0016740molecular_functiontransferase activity
C0030855biological_processepithelial cell differentiation
C0043231cellular_componentintracellular membrane-bounded organelle
C0070062cellular_componentextracellular exosome
C0098869biological_processcellular oxidant detoxification
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING: BINDING => ECO:0000269|PubMed:16081649
ChainResidueDetails
ASER16
CASN53
CLEU183
CSER200
AASN53
ALEU183
ASER200
BSER16
BASN53
BLEU183
BSER200
CSER16

site_idSWS_FT_FI2
Number of Residues6
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q9DCM2
ChainResidueDetails
ALYS49
ALYS144
BLYS49
BLYS144
CLYS49
CLYS144

site_idSWS_FT_FI3
Number of Residues6
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
ALYS71
ALYS169
BLYS71
BLYS169
CLYS71
CLYS169

site_idSWS_FT_FI4
Number of Residues6
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9DCM2
ChainResidueDetails
ALYS85
ALYS165
BLYS85
BLYS165
CLYS85
CLYS165

site_idSWS_FT_FI5
Number of Residues6
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q9DCM2
ChainResidueDetails
ALYS116
ALYS158
BLYS116
BLYS158
CLYS116
CLYS158

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PDB entries from 2024-07-17

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