Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3ROJ

D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase of Synechocystis sp. PCC 6803

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006071	biological_process	glycerol metabolic process
A	0006094	biological_process	gluconeogenesis
A	0016787	molecular_function	hydrolase activity
A	0019253	biological_process	reductive pentose-phosphate cycle
A	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
A	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
A	0046872	molecular_function	metal ion binding
A	0050278	molecular_function	sedoheptulose-bisphosphatase activity
B	0006071	biological_process	glycerol metabolic process
B	0006094	biological_process	gluconeogenesis
B	0016787	molecular_function	hydrolase activity
B	0019253	biological_process	reductive pentose-phosphate cycle
B	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
B	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
B	0046872	molecular_function	metal ion binding
B	0050278	molecular_function	sedoheptulose-bisphosphatase activity
C	0006071	biological_process	glycerol metabolic process
C	0006094	biological_process	gluconeogenesis
C	0016787	molecular_function	hydrolase activity
C	0019253	biological_process	reductive pentose-phosphate cycle
C	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
C	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
C	0046872	molecular_function	metal ion binding
C	0050278	molecular_function	sedoheptulose-bisphosphatase activity
D	0006071	biological_process	glycerol metabolic process
D	0006094	biological_process	gluconeogenesis
D	0016787	molecular_function	hydrolase activity
D	0019253	biological_process	reductive pentose-phosphate cycle
D	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
D	0042132	molecular_function	fructose 1,6-bisphosphate 1-phosphatase activity
D	0046872	molecular_function	metal ion binding
D	0050278	molecular_function	sedoheptulose-bisphosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 346

Chain	Residue
A	ASP97
A	GLU100
A	GLU225
A	CL361
A	HOH495

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 347

Chain	Residue
A	CYS99
A	HOH495
A	ASP33
A	GLU57
A	ASP97
A	PRO98

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE AMP A 348

Chain	Residue
A	ARG307
A	PHE309
A	ARG314
A	VAL341
A	ILE342
A	GLN343
A	HIS345
A	HOH382
A	HOH386
A	HOH425
A	HOH446
A	HOH452
A	HOH782
B	ARG164
B	GLY211
B	THR212
B	ASN213
B	HIS215

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 349

Chain	Residue
A	TYR131
A	ARG176
A	ARG178

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 350

Chain	Residue
A	ARG176
A	PRO177
A	ARG178
A	VAL251
A	HOH849

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 351

Chain	Residue
A	ASN163
A	HOH612
A	HOH758
A	HOH878
B	HIS310

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 352

Chain	Residue
A	HIS310
B	ASN163

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 353

Chain	Residue
A	LYS26
B	ARG60

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 354

Chain	Residue
A	ARG60
A	HOH467
B	LYS26
B	HOH637

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 355

Chain	Residue
A	ARG234
A	ALA285
A	CSO286
A	GLY287
A	VAL290

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 356

Chain	Residue
A	GLU71
A	HOH768

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 357

Chain	Residue
A	ASN110
B	ASN110
B	HOH539

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 358

Chain	Residue
A	ASP200
A	ALA222
A	HOH577

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 359

Chain	Residue
A	GLU181
A	HOH590

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 361

Chain	Residue
A	GLY101
A	THR102
A	ASP198
A	MG346

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 362

Chain	Residue
A	ARG52
A	HOH431
A	HOH596

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 363

Chain	Residue
A	GLN241
A	ASN280
A	HOH427
A	HOH678

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 365

Chain	Residue
A	LYS142
A	GLY143
A	HIS239
A	PHE240
A	ASN280
A	CYS281
D	HOH414
D	HOH719

site_id	CC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE AMP B 348

Chain	Residue
B	HOH398
B	HOH410
B	HOH462
B	HOH464
A	ARG164
A	GLY211
A	THR212
A	ASN213
A	HIS215
B	ARG307
B	PHE309
B	ARG314
B	VAL341
B	ILE342
B	GLN343
B	HIS345
B	HOH368
B	HOH386
B	HOH396

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 346

Chain	Residue
B	ASP97
B	GLU100
B	GLU225

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 347

Chain	Residue
B	ASP33
B	GLU57
B	ASP97
B	PRO98
B	CYS99
B	HOH409

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 349

Chain	Residue
B	TYR131
B	ARG176
B	ARG178

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 350

Chain	Residue
B	ARG176
B	PRO177
B	ARG178
B	VAL251

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL B 351

Chain	Residue
B	TYR67
B	GLU70
B	GLU71
B	HOH538
B	HOH600
B	HOH842

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 353

Chain	Residue
B	PRO177
B	ARG178

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 354

Chain	Residue
B	GLY101
B	THR102

site_id	CC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 346

Chain	Residue
C	ASP97
C	GLU100
C	GLU225
C	SO4352
C	HOH408

site_id	DC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 347

Chain	Residue
C	ASP33
C	GLU57
C	ASP97
C	PRO98
C	CYS99
C	HOH408

site_id	DC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP C 348

Chain	Residue
C	ARG164
C	GLY211
C	THR212
C	ASN213
C	HIS215
C	HOH388
C	HOH426
C	HOH428
C	HOH450
C	HOH536
D	ARG307
D	PHE309
D	ARG314
D	VAL341
D	ILE342
D	GLN343
D	HIS345

site_id	DC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE AMP C 349

Chain	Residue
C	ARG307
C	PHE309
C	ARG314
C	VAL341
C	ILE342
C	GLN343
C	HIS345
C	HOH405
C	HOH422
C	HOH439
C	HOH457
D	ARG164
D	GLY211
D	THR212
D	ASN213
D	HIS215

site_id	DC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 350

Chain	Residue
C	TYR131
C	MET174
C	ARG176
C	ARG178
C	HOH463
C	HOH865

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 351

Chain	Residue
C	ARG176
C	PRO177
C	ARG178
C	VAL251
C	HOH463

site_id	DC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 352

Chain	Residue
C	CYS99
C	GLY101
C	THR102
C	MG346
C	HOH408
C	HOH465

site_id	DC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 353

Chain	Residue
C	HIS310
C	LYS340
C	HOH381
D	ASN163

site_id	DC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 354

Chain	Residue
B	HOH593
C	SER324
C	THR326

site_id	DC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 355

Chain	Residue
C	GLY237
C	HOH757

site_id	EC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 356

Chain	Residue
C	LYS142
C	PHE240
C	CYS281

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 357

Chain	Residue
C	HOH419
C	HOH421

site_id	EC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 358

Chain	Residue
C	ASP129

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 359

Chain	Residue
C	ASN110

site_id	EC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 346

Chain	Residue
D	ASP97
D	GLU100
D	GLU225
D	SO4350

site_id	EC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 347

Chain	Residue
D	ASP33
D	GLU57
D	ASP97
D	PRO98
D	CYS99
D	HOH395

site_id	EC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 348

Chain	Residue
D	TYR131
D	ARG176
D	ARG178
D	HOH829

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 349

Chain	Residue
D	ARG176
D	PRO177
D	ARG178
D	VAL251

site_id	EC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 D 350

Chain	Residue
D	CYS99
D	GLY101
D	THR102
D	MG346
D	HOH387
D	HOH395
D	HOH444
D	HOH804

site_id	FC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 351

Chain	Residue
C	ASN163
D	HIS310
D	LYS340
D	HOH605

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 352

Chain	Residue
D	ASP129
D	TYR131

site_id	FC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 353

Chain	Residue
D	GLU337
D	HOH599

site_id	FC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 354

Chain	Residue
D	HOH703

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP33
B	GLU57
B	ASP97
B	GLU100
B	TYR131
B	ARG176
B	ASP198
B	GLU225
C	ASP33
C	GLU57
C	ASP97
A	GLU57
C	GLU100
C	TYR131
C	ARG176
C	ASP198
C	GLU225
D	ASP33
D	GLU57
D	ASP97
D	GLU100
D	TYR131
A	ASP97
D	ARG176
D	ASP198
D	GLU225
A	GLU100
A	TYR131
A	ARG176
A	ASP198
A	GLU225
B	ASP33

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)