3ROI
2.20 Angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003866 | molecular_function | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 439 |
| Chain | Residue |
| A | MET45 |
| A | ASN70 |
| A | PHE415 |
| A | PRO416 |
| A | ASN417 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 440 |
| Chain | Residue |
| A | THR96 |
| A | ARG123 |
| A | LYS21 |
| A | ASN93 |
| A | SER94 |
| A | GLY95 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 441 |
| Chain | Residue |
| A | ARG406 |
| A | ASN407 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 442 |
| Chain | Residue |
| A | THR262 |
| A | ARG263 |
| A | LEU264 |
| A | GLN309 |
| A | LEU312 |
| A | HOH566 |
| B | LYS271 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 443 |
| Chain | Residue |
| A | GLY143 |
| B | LYS330 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 444 |
| Chain | Residue |
| A | HIS160 |
| A | GLY183 |
| A | LYS184 |
| A | HOH489 |
| B | LYS222 |
| B | LYS224 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 445 |
| Chain | Residue |
| A | LYS356 |
| A | ASN381 |
| A | ARG406 |
| B | GLN58 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 446 |
| Chain | Residue |
| A | ARG99 |
| A | ARG123 |
| A | ARG127 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 447 |
| Chain | Residue |
| A | SER22 |
| A | ARG26 |
| A | THR96 |
| A | GLN169 |
| A | HOH520 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 448 |
| Chain | Residue |
| A | GLY329 |
| A | LYS330 |
| A | GLN371 |
| A | HOH567 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 449 |
| Chain | Residue |
| A | HIS297 |
| A | ARG299 |
| A | HOH561 |
| A | HOH572 |
| B | ARG299 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 450 |
| Chain | Residue |
| A | ASP68 |
| A | PRO124 |
| A | LYS126 |
| A | ARG127 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 439 |
| Chain | Residue |
| B | MET45 |
| B | ASN70 |
| B | PHE415 |
| B | PRO416 |
| B | ASN417 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 440 |
| Chain | Residue |
| B | SER172 |
| B | ARG194 |
| B | HIS196 |
| B | THR197 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 441 |
| Chain | Residue |
| B | SER167 |
| B | ALA168 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 442 |
| Chain | Residue |
| A | LYS271 |
| B | THR262 |
| B | ARG263 |
| B | LEU264 |
| B | GLN309 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 443 |
| Chain | Residue |
| B | SER22 |
| B | ARG26 |
| B | THR96 |
| B | ARG99 |
| B | GLN169 |
| B | ARG194 |
| B | HOH505 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 444 |
| Chain | Residue |
| A | LYS222 |
| B | LYS184 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 445 |
| Chain | Residue |
| B | ARG99 |
| B | ARG123 |
| B | GLN169 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 446 |
| Chain | Residue |
| B | ASN93 |
| B | SER94 |
| B | GLY95 |
| B | THR96 |
| B | ARG99 |
| B | ARG123 |
| B | HOH452 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00210 |
| Chain | Residue | Details |
| A | ASP315 | |
| B | ASP315 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000269|Ref.4, ECO:0007744|PDB:4EGR |
| Chain | Residue | Details |
| A | LYS21 | |
| B | THR96 | |
| B | ARG123 | |
| B | GLN169 | |
| B | ARG346 | |
| B | ARG387 | |
| A | GLY95 | |
| A | THR96 | |
| A | ARG123 | |
| A | GLN169 | |
| A | ARG346 | |
| A | ARG387 | |
| B | LYS21 | |
| B | GLY95 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3, ECO:0000269|Ref.7, ECO:0007744|PDB:3SLH, ECO:0007744|PDB:4ZND |
| Chain | Residue | Details |
| A | SER22 | |
| B | ALA168 | |
| B | ASP315 | |
| B | LYS342 | |
| A | ARG26 | |
| A | SER167 | |
| A | ALA168 | |
| A | ASP315 | |
| A | LYS342 | |
| B | SER22 | |
| B | ARG26 | |
| B | SER167 |
