3ROF

Crystal Structure of the S. aureus Protein Tyrosine Phosphatase PtpA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0005576	cellular_component	extracellular region
A	0006470	biological_process	protein dephosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 A 201

Chain	Residue
A	CYS8
B	HIS49
A	LEU9
A	GLY10
A	ASN11
A	ILE12
A	CYS13
A	ARG14
A	ASP120
A	TYR122

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 A 202

Chain	Residue
A	HIS37
A	ARG39
A	GLU71
A	HOH527
A	HOH581
A	HOH582

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P11064

Chain	Residue	Details
A	CYS8

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P11064

Chain	Residue	Details
A	ARG14

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P11064

Chain	Residue	Details
A	ASP120

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