Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3ROE

Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with Thymidine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002040	biological_process	sprouting angiogenesis
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0005929	cellular_component	cilium
A	0006869	biological_process	lipid transport
A	0010874	biological_process	regulation of cholesterol efflux
A	0016525	biological_process	negative regulation of angiogenesis
A	0016853	molecular_function	isomerase activity
A	0031580	biological_process	membrane raft distribution
A	0042802	molecular_function	identical protein binding
A	0044297	cellular_component	cell body
A	0046496	biological_process	nicotinamide nucleotide metabolic process
A	0046872	molecular_function	metal ion binding
A	0052856	molecular_function	NAD(P)HX epimerase activity
A	0110051	biological_process	metabolite repair
B	0000166	molecular_function	nucleotide binding
B	0002040	biological_process	sprouting angiogenesis
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0005929	cellular_component	cilium
B	0006869	biological_process	lipid transport
B	0010874	biological_process	regulation of cholesterol efflux
B	0016525	biological_process	negative regulation of angiogenesis
B	0016853	molecular_function	isomerase activity
B	0031580	biological_process	membrane raft distribution
B	0042802	molecular_function	identical protein binding
B	0044297	cellular_component	cell body
B	0046496	biological_process	nicotinamide nucleotide metabolic process
B	0046872	molecular_function	metal ion binding
B	0052856	molecular_function	NAD(P)HX epimerase activity
B	0110051	biological_process	metabolite repair
C	0000166	molecular_function	nucleotide binding
C	0002040	biological_process	sprouting angiogenesis
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0005929	cellular_component	cilium
C	0006869	biological_process	lipid transport
C	0010874	biological_process	regulation of cholesterol efflux
C	0016525	biological_process	negative regulation of angiogenesis
C	0016853	molecular_function	isomerase activity
C	0031580	biological_process	membrane raft distribution
C	0042802	molecular_function	identical protein binding
C	0044297	cellular_component	cell body
C	0046496	biological_process	nicotinamide nucleotide metabolic process
C	0046872	molecular_function	metal ion binding
C	0052856	molecular_function	NAD(P)HX epimerase activity
C	0110051	biological_process	metabolite repair
D	0000166	molecular_function	nucleotide binding
D	0002040	biological_process	sprouting angiogenesis
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0005929	cellular_component	cilium
D	0006869	biological_process	lipid transport
D	0010874	biological_process	regulation of cholesterol efflux
D	0016525	biological_process	negative regulation of angiogenesis
D	0016853	molecular_function	isomerase activity
D	0031580	biological_process	membrane raft distribution
D	0042802	molecular_function	identical protein binding
D	0044297	cellular_component	cell body
D	0046496	biological_process	nicotinamide nucleotide metabolic process
D	0046872	molecular_function	metal ion binding
D	0052856	molecular_function	NAD(P)HX epimerase activity
D	0110051	biological_process	metabolite repair
E	0000166	molecular_function	nucleotide binding
E	0002040	biological_process	sprouting angiogenesis
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005739	cellular_component	mitochondrion
E	0005829	cellular_component	cytosol
E	0005929	cellular_component	cilium
E	0006869	biological_process	lipid transport
E	0010874	biological_process	regulation of cholesterol efflux
E	0016525	biological_process	negative regulation of angiogenesis
E	0016853	molecular_function	isomerase activity
E	0031580	biological_process	membrane raft distribution
E	0042802	molecular_function	identical protein binding
E	0044297	cellular_component	cell body
E	0046496	biological_process	nicotinamide nucleotide metabolic process
E	0046872	molecular_function	metal ion binding
E	0052856	molecular_function	NAD(P)HX epimerase activity
E	0110051	biological_process	metabolite repair
F	0000166	molecular_function	nucleotide binding
F	0002040	biological_process	sprouting angiogenesis
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005739	cellular_component	mitochondrion
F	0005829	cellular_component	cytosol
F	0005929	cellular_component	cilium
F	0006869	biological_process	lipid transport
F	0010874	biological_process	regulation of cholesterol efflux
F	0016525	biological_process	negative regulation of angiogenesis
F	0016853	molecular_function	isomerase activity
F	0031580	biological_process	membrane raft distribution
F	0042802	molecular_function	identical protein binding
F	0044297	cellular_component	cell body
F	0046496	biological_process	nicotinamide nucleotide metabolic process
F	0046872	molecular_function	metal ion binding
F	0052856	molecular_function	NAD(P)HX epimerase activity
F	0110051	biological_process	metabolite repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE THM A 265

Chain	Residue
A	ALA35
A	LEU211
A	THR212
A	LYS215
A	VAL38
A	ASP39
A	LEU53
A	MSE54
A	ASN89
A	ASP93
A	PHE160
A	ASP188

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE THM B 265

Chain	Residue
B	ALA35
B	ASP39
B	LEU53
B	MSE54
B	ASP93
B	PHE160
B	ASP188
B	LEU211
B	THR212
B	LYS215
B	HOH337
B	HOH476

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE THM C 265

Chain	Residue
C	ALA35
C	VAL38
C	ASP39
C	LEU53
C	MSE54
C	ASP93
C	PHE160
C	ASP188
C	LEU211
C	THR212
C	LYS215

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE THM D 265

Chain	Residue
D	ALA35
D	ASP39
D	PHE43
D	LEU53
D	ASP93
D	PHE160
D	ASP188
D	LEU211
D	THR212
D	LYS215
D	HOH370
D	HOH371

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE THM E 265

Chain	Residue
E	ALA35
E	VAL38
E	ASP39
E	LEU53
E	MSE54
E	ASP93
E	PHE160
E	ASP188
E	LEU211
E	THR212
E	LYS215
E	HOH477

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE THM F 265

Chain	Residue
F	ALA35
F	ASP39
F	PHE43
F	LEU53
F	ASP93
F	PHE160
F	ASP188
F	LEU211
F	THR212
F	LYS215
F	HOH280
F	HOH474

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	6
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)