3RMW
Crystal Structure of Human Glycogenin-1 (GYG1) T83M mutant complexed with manganese and UDP-glucose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE UPG A 263 |
| Chain | Residue |
| A | LEU9 |
| A | ASN133 |
| A | SER134 |
| A | GLY135 |
| A | ASP160 |
| A | GLY162 |
| A | ASP163 |
| A | GLN164 |
| A | HIS212 |
| A | LEU214 |
| A | GLY215 |
| A | THR10 |
| A | LYS218 |
| A | MN264 |
| A | EDO270 |
| A | HOH309 |
| A | HOH343 |
| A | HOH352 |
| A | HOH399 |
| A | HOH400 |
| A | HOH404 |
| A | HOH405 |
| A | THR11 |
| A | HOH461 |
| A | HOH466 |
| A | ASN12 |
| A | TYR15 |
| A | LYS86 |
| A | ASP102 |
| A | ALA103 |
| A | ASP104 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 264 |
| Chain | Residue |
| A | ASP102 |
| A | ASP104 |
| A | HIS212 |
| A | UPG263 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 265 |
| Chain | Residue |
| A | ASP3 |
| A | GLN94 |
| A | HIS151 |
| A | GLU155 |
| A | HOH417 |
| A | HOH418 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 266 |
| Chain | Residue |
| A | VAL61 |
| A | HIS88 |
| A | SER91 |
| A | LEU92 |
| A | HOH340 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 267 |
| Chain | Residue |
| A | THR93 |
| A | VAL143 |
| A | HOH293 |
| A | HOH446 |
| A | HOH447 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 268 |
| Chain | Residue |
| A | PRO124 |
| A | PRO129 |
| A | PRO129 |
| A | ASP130 |
| A | HIS182 |
| A | HIS182 |
| A | HOH348 |
| A | HOH348 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 269 |
| Chain | Residue |
| A | GLU119 |
| A | LEU120 |
| A | SER173 |
| A | TRP174 |
| A | LYS181 |
| A | HOH312 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 270 |
| Chain | Residue |
| A | VAL82 |
| A | LYS86 |
| A | GLY161 |
| A | ASP163 |
| A | UPG263 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 271 |
| Chain | Residue |
| A | THR2 |
| A | GLN94 |
| A | GLN148 |
| A | HIS151 |
| A | HOH334 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 272 |
| Chain | Residue |
| A | PHE170 |
| A | PHE171 |
| A | HOH283 |
| A | HOH356 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 273 |
| Chain | Residue |
| A | ASP56 |
| A | GLU57 |
| A | VAL58 |
| A | HOH436 |
| A | HOH438 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 274 |
| Chain | Residue |
| A | PRO41 |
| A | ASP62 |
| A | GLN262 |
| A | HOH336 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 275 |
| Chain | Residue |
| A | ASP45 |
| A | LYS49 |
| A | GLU52 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 276 |
| Chain | Residue |
| A | ASP65 |
| A | SER66 |
| A | HOH371 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 277 |
| Chain | Residue |
| A | ASP56 |
| A | GLU144 |
| A | HOH439 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22160680","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3RMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3T7O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P13280","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22160680","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3T7O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3RMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3T7O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"UniProtKB","id":"P13280","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P13280","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
