3RL5
Rat metallophosphodiesterase MPPED2 H67R Mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004112 | molecular_function | cyclic-nucleotide phosphodiesterase activity |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0016208 | molecular_function | AMP binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019002 | molecular_function | GMP binding |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 666 |
| Chain | Residue |
| A | GLU147 |
| A | GLU147 |
| A | ASP150 |
| A | ASP150 |
| A | ASN151 |
| A | HOH475 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 888 |
| Chain | Residue |
| A | PRO279 |
| A | HOH570 |
| A | CYS273 |
| A | PHE277 |
| A | GLN278 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 999 |
| Chain | Residue |
| A | THR27 |
| A | LEU90 |
| A | PHE138 |
| A | PRO139 |
| A | SER140 |
| A | VAL141 |
| A | HOH320 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 777 |
| Chain | Residue |
| A | TRP179 |
| A | THR180 |
| A | PRO181 |
| A | THR212 |
| A | HIS213 |
| A | GLY214 |
| A | PRO215 |
| A | LEU235 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21824479","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3RL3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RL4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
