3RK8
Crystal structure of the chloride inhibited dihydrodipicolinate synthase from Acinetobacter baumannii complexed with pyruvate at 1.8 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0044281 | biological_process | small molecule metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019877 | biological_process | diaminopimelate biosynthetic process |
| B | 0044281 | biological_process | small molecule metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PYR A 292 |
| Chain | Residue |
| A | TYR133 |
| A | HOH594 |
| A | VAL135 |
| A | ARG138 |
| A | LYS161 |
| A | GLY186 |
| A | VAL205 |
| A | ASN248 |
| A | HOH415 |
| A | HOH419 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 293 |
| Chain | Residue |
| A | LYS15 |
| A | THR264 |
| A | GLY265 |
| A | ILE266 |
| A | PRO272 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 294 |
| Chain | Residue |
| A | GLN3 |
| A | GLY4 |
| A | ASN37 |
| A | ALA219 |
| A | ILE222 |
| A | HOH352 |
| A | HOH447 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 295 |
| Chain | Residue |
| A | ASP20 |
| A | TRP21 |
| A | LYS22 |
| A | HOH424 |
| A | HOH438 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 296 |
| Chain | Residue |
| A | GLU54 |
| A | GLU55 |
| A | GLN58 |
| A | HOH436 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 297 |
| Chain | Residue |
| A | GLU25 |
| A | ARG65 |
| A | HOH420 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 298 |
| Chain | Residue |
| A | ASP16 |
| A | ARG267 |
| A | HOH404 |
| A | HOH443 |
| A | HOH445 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 299 |
| Chain | Residue |
| A | THR44 |
| A | LEU101 |
| A | LYS161 |
| A | HOH403 |
| A | HOH417 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PYR B 292 |
| Chain | Residue |
| B | TYR133 |
| B | VAL135 |
| B | ARG138 |
| B | LYS161 |
| B | GLY186 |
| B | VAL205 |
| B | ASN248 |
| B | HOH425 |
| B | HOH428 |
| B | HOH605 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 293 |
| Chain | Residue |
| B | LYS15 |
| B | THR264 |
| B | GLY265 |
| B | ILE266 |
| B | PRO272 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 294 |
| Chain | Residue |
| B | ALA182 |
| B | ASP200 |
| B | GOL295 |
| B | HOH377 |
| B | HOH387 |
| B | HOH576 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 295 |
| Chain | Residue |
| B | MET195 |
| B | GLY198 |
| B | ALA199 |
| B | ILE222 |
| B | LYS224 |
| B | GOL294 |
| B | HOH576 |
| B | HOH578 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 296 |
| Chain | Residue |
| B | GLY165 |
| B | ASP187 |
| B | GLU189 |
| B | HOH474 |
| B | HOH557 |
| B | HOH590 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG B 297 |
| Chain | Residue |
| B | TRP21 |
| B | GLN58 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 298 |
| Chain | Residue |
| B | LEU101 |
| B | LYS161 |
| B | HOH401 |
| B | HOH427 |
| B | HOH599 |
Functional Information from PROSITE/UniProt
