Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004802 | molecular_function | transketolase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004802 | molecular_function | transketolase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004802 | molecular_function | transketolase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004802 | molecular_function | transketolase activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005829 | cellular_component | cytosol |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006098 | biological_process | pentose-phosphate shunt |
| D | 0009274 | cellular_component | peptidoglycan-based cell wall |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1001 |
| Chain | Residue |
| A | ASP177 |
| A | ASN207 |
| A | ILE209 |
| A | HOH779 |
| A | TPP1002 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE TPP A 1002 |
| Chain | Residue |
| A | SER176 |
| A | ASP177 |
| A | GLY178 |
| A | GLU182 |
| A | ASN207 |
| A | ILE209 |
| A | SER210 |
| A | ILE211 |
| A | HIS283 |
| A | HOH779 |
| A | MG1001 |
| C | ASP401 |
| C | GLU441 |
| C | PHE467 |
| C | TYR470 |
| C | HIS503 |
| C | HOH748 |
| A | THR48 |
| A | HIS85 |
| A | GLY133 |
| A | LEU135 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1001 |
| Chain | Residue |
| B | ASP177 |
| B | ASN207 |
| B | ILE209 |
| B | HOH819 |
| B | TPP1002 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE TPP B 1002 |
| Chain | Residue |
| B | THR48 |
| B | HIS85 |
| B | GLY133 |
| B | LEU135 |
| B | SER176 |
| B | ASP177 |
| B | GLY178 |
| B | GLU182 |
| B | ASN207 |
| B | ILE209 |
| B | SER210 |
| B | ILE211 |
| B | ILE269 |
| B | HIS283 |
| B | HOH819 |
| B | MG1001 |
| D | ASP401 |
| D | GLU441 |
| D | PHE467 |
| D | TYR470 |
| D | HIS503 |
| D | HOH811 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 701 |
| Chain | Residue |
| B | ILE7 |
| B | SER8 |
| B | ALA9 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 702 |
| Chain | Residue |
| B | CYS220 |
| D | TYR230 |
| D | GLY231 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 1001 |
| Chain | Residue |
| C | ASP177 |
| C | ASN207 |
| C | ILE209 |
| C | HOH760 |
| C | TPP1002 |
| site_id | AC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE TPP C 1002 |
| Chain | Residue |
| A | ASP401 |
| A | GLU441 |
| A | PHE467 |
| A | TYR470 |
| A | HIS503 |
| C | THR48 |
| C | HIS85 |
| C | GLY133 |
| C | PRO134 |
| C | LEU135 |
| C | SER176 |
| C | ASP177 |
| C | GLY178 |
| C | GLU182 |
| C | ASN207 |
| C | ILE209 |
| C | SER210 |
| C | ILE269 |
| C | HIS283 |
| C | HOH747 |
| C | HOH760 |
| C | MG1001 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 701 |
| Chain | Residue |
| C | TRP430 |
| C | TYR431 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 702 |
| Chain | Residue |
| B | HIS15 |
| B | HOH830 |
| C | ARG123 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 1001 |
| Chain | Residue |
| D | ASP177 |
| D | ASN207 |
| D | ILE209 |
| D | HOH838 |
| D | TPP1002 |
| site_id | BC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE TPP D 1002 |
| Chain | Residue |
| B | PHE467 |
| B | TYR470 |
| B | HIS503 |
| D | THR48 |
| D | HIS85 |
| D | GLY133 |
| D | LEU135 |
| D | SER176 |
| D | ASP177 |
| D | GLY178 |
| D | GLU182 |
| D | ASN207 |
| D | ILE209 |
| D | SER210 |
| D | ILE269 |
| D | HIS283 |
| D | HOH738 |
| D | HOH838 |
| D | HOH840 |
| D | MG1001 |
| B | ASP401 |
| B | VAL439 |
| B | GLU441 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 701 |
| Chain | Residue |
| D | ARG378 |
| D | SER405 |
| D | HIS491 |
| D | ARG552 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 702 |
| Chain | Residue |
| D | ALA403 |
| D | ASN407 |
| D | THR409 |
| D | TYR426 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 703 |
| Chain | Residue |
| B | ARG351 |
| B | LYS356 |
| D | ASP17 |
| D | TYR18 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 704 |
| Chain | Residue |
| D | PHE122 |
| D | VAL452 |
| D | ASP484 |
Functional Information from PROSITE/UniProt
| site_id | PS00801 |
| Number of Residues | 21 |
| Details | TRANSKETOLASE_1 Transketolase signature 1. RvlaADavqkvgNGHPGtaMS |
| Chain | Residue | Details |
| A | ARG31-SER51 | |
| site_id | PS00802 |
| Number of Residues | 17 |
| Details | TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPIEhlSalR |
| Chain | Residue | Details |
| A | GLY497-ARG513 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| A | GLU441 | |
| B | GLU441 | |
| C | GLU441 | |
| D | GLU441 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS45 | |
| B | HIS491 | |
| B | ASP499 | |
| B | ARG552 | |
| C | HIS45 | |
| C | ARG378 | |
| C | SER405 | |
| C | HIS491 | |
| C | ASP499 | |
| C | ARG552 | |
| D | HIS45 | |
| A | ARG378 | |
| D | ARG378 | |
| D | SER405 | |
| D | HIS491 | |
| D | ASP499 | |
| D | ARG552 | |
| A | SER405 | |
| A | HIS491 | |
| A | ASP499 | |
| A | ARG552 | |
| B | HIS45 | |
| B | ARG378 | |
| B | SER405 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | THR48 | |
| B | HIS85 | |
| B | GLY133 | |
| B | LEU135 | |
| B | GLY178 | |
| B | ASN207 | |
| B | HIS283 | |
| B | PHE467 | |
| C | THR48 | |
| C | HIS85 | |
| C | GLY133 | |
| A | HIS85 | |
| C | LEU135 | |
| C | GLY178 | |
| C | ASN207 | |
| C | HIS283 | |
| C | PHE467 | |
| D | THR48 | |
| D | HIS85 | |
| D | GLY133 | |
| D | LEU135 | |
| D | GLY178 | |
| A | GLY133 | |
| D | ASN207 | |
| D | HIS283 | |
| D | PHE467 | |
| A | LEU135 | |
| A | GLY178 | |
| A | ASN207 | |
| A | HIS283 | |
| A | PHE467 | |
| B | THR48 | |
| Chain | Residue | Details |
| A | ASP177 | |
| A | ILE209 | |
| B | ASP177 | |
| B | ILE209 | |
| C | ASP177 | |
| C | ILE209 | |
| D | ASP177 | |
| D | ILE209 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | SITE: Important for catalytic activity => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS45 | |
| A | HIS283 | |
| B | HIS45 | |
| B | HIS283 | |
| C | HIS45 | |
| C | HIS283 | |
| D | HIS45 | |
| D | HIS283 | |
| Chain | Residue | Details |
| A | THR2 | |
| B | THR2 | |
| C | THR2 | |
| D | THR2 | |
