Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000118 | cellular_component | histone deacetylase complex |
A | 0000166 | molecular_function | nucleotide binding |
A | 0003824 | molecular_function | catalytic activity |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0006508 | biological_process | proteolysis |
A | 0006915 | biological_process | apoptotic process |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
A | 0009154 | biological_process | purine ribonucleotide catabolic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016926 | biological_process | protein desumoylation |
A | 0016929 | molecular_function | deSUMOylase activity |
A | 0043530 | molecular_function | adenosine 5'-monophosphoramidase activity |
A | 0072332 | biological_process | intrinsic apoptotic signaling pathway by p53 class mediator |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE 5GP A 201 |
Chain | Residue |
A | ASN99 |
A | GLY105 |
A | GLN106 |
A | SER107 |
A | VAL108 |
A | HIS112 |
A | HIS114 |
A | HOH219 |
A | HOH235 |
A | PHE19 |
A | PHE41 |
A | HIS42 |
A | ASP43 |
A | ILE44 |
A | LEU53 |
site_id | HIT |
Number of Residues | 3 |
Details | THE HISTIDINE TRIAD FORMS PART OF THE ALPHA PHOSPHATE-BINDING LOOP IN THE HIT PROTEIN SUPERFAMILY OF NUCLEOTIDE-BINDING PROTEINS. |
Chain | Residue |
A | HIS110 |
A | HIS112 |
A | HIS114 |
Functional Information from PROSITE/UniProt
site_id | PS00892 |
Number of Residues | 19 |
Details | HIT_1 HIT domain signature. NegsdGgQsVyHVHLHVLG |
Chain | Residue | Details |
A | ASN99-GLY117 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | LEU113 | |
Chain | Residue | Details |
A | ILE44 | |
A | GLU100 | |
A | GLN106 | |
A | LEU113 | |
Chain | Residue | Details |
A | ILE22 | |
A | ILE31 | |
Chain | Residue | Details |
A | PRO46 | |
A | LEU73 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 5fit |
Chain | Residue | Details |
A | HIS112 | |
A | ASN99 | |
A | HIS110 | |