3RG8

Crystal structure of Treponema denticola PurE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006189	biological_process	'de novo' IMP biosynthetic process
A	0016829	molecular_function	lyase activity
A	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity
B	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0006189	biological_process	'de novo' IMP biosynthetic process
B	0016829	molecular_function	lyase activity
B	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity
C	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0006189	biological_process	'de novo' IMP biosynthetic process
C	0016829	molecular_function	lyase activity
C	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity
D	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0006189	biological_process	'de novo' IMP biosynthetic process
D	0016829	molecular_function	lyase activity
D	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity
E	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
E	0006164	biological_process	purine nucleotide biosynthetic process
E	0006189	biological_process	'de novo' IMP biosynthetic process
E	0016829	molecular_function	lyase activity
E	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity
F	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
F	0006164	biological_process	purine nucleotide biosynthetic process
F	0006189	biological_process	'de novo' IMP biosynthetic process
F	0016829	molecular_function	lyase activity
F	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity
G	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
G	0006164	biological_process	purine nucleotide biosynthetic process
G	0006189	biological_process	'de novo' IMP biosynthetic process
G	0016829	molecular_function	lyase activity
G	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity
H	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
H	0006164	biological_process	purine nucleotide biosynthetic process
H	0006189	biological_process	'de novo' IMP biosynthetic process
H	0016829	molecular_function	lyase activity
H	0043727	molecular_function	5-amino-4-imidazole carboxylate lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 160

Chain	Residue
D	PRO89
D	PRO90
D	SER91
D	GLY96
D	HOH229

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO H 160

Chain	Residue
H	HOH192
H	HOH204
H	PRO89
H	PRO90
H	SER91
H	GLY96

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02045, ECO:0000269|PubMed:21548610, ECO:0007744|PDB:3RGG

Chain	Residue	Details
A	SER11
A	ASP14
A	SER38
A	LYS41
F	SER38
F	LYS41
F	GLY67
F	SER69
G	SER11
G	ASP14
G	SER38
G	LYS41
G	GLY67
G	SER69
H	SER11
H	ASP14
H	SER38
H	LYS41
H	GLY67
H	SER69
A	GLY67
A	SER69
B	SER11
B	ASP14
B	SER38
B	LYS41
B	GLY67
B	SER69
C	SER11
C	ASP14
C	SER38
C	LYS41
C	GLY67
C	SER69
D	SER11
D	ASP14
D	SER38
D	LYS41
D	GLY67
D	SER69
E	SER11
E	ASP14
E	SER38
E	LYS41
E	GLY67
E	SER69
F	SER11
F	ASP14

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