3RCI

Human cyclophilin D complexed with 5-methyl-1,2-oxazol-3-amine

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0000413	biological_process	protein peptidyl-prolyl isomerization
X	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
X	0006457	biological_process	protein folding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE M3I X 1

Chain	Residue
X	ARG97
X	ALA143
X	ASN144
X	HIS168
X	M3I208
X	HOH228

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE M3I X 208

Chain	Residue
X	GLN105
X	ASN113
X	GLY114
X	THR131
X	M3I209
X	M3I1
X	HIS96
X	ARG97

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site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE M3I X 209

Chain	Residue
X	GLN105
X	GLY114
X	ARG124
X	ALA143
X	ASN144
X	THR149
X	GLN153
X	M3I208
X	HOH339
X	HOH361
X	HOH449

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE M3I X 210

Chain	Residue
X	VAL135
X	GLY136
X	PRO137
X	HIS173
X	HOH300
X	HOH301

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Functional Information from PROSITE/UniProt

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIpsFMcQAG

Chain	Residue	Details
X	TYR90-GLY107

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
X	LYS67

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site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
X	LYS86
X	ILE175
X	LYS190

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
X	LYS167

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: S-nitrosocysteine => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
X	CYS203

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