3RCF

Human cyclophilin D complexed with N-[(4-aminophenyl)sulfonyl]benzamide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000413	biological_process	protein peptidyl-prolyl isomerization
A	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
A	0006457	biological_process	protein folding

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE BS4 A 1

Chain	Residue
A	ASN55
A	HOH324
A	HOH403
A	HOH406
A	HOH407
A	HOH408
A	HOH434
A	HOH532
A	HOH533
A	HOH556
A	HOH557
A	GLY56
A	HOH573
A	HOH574
A	HOH575
A	HOH586
A	LYS57
A	PHE102
A	GLN105
A	PHE155
A	TRP163
A	LEU164
A	HOH210

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site_id	AC2
Number of Residues	23
Details	BINDING SITE FOR RESIDUE BS4 A 208

Chain	Residue
A	LYS57
A	ASP127
A	GLU128
A	ASN129
A	PHE130
A	THR131
A	ASN144
A	ALA145
A	HOH244
A	HOH270
A	HOH272
A	HOH304
A	HOH375
A	HOH407
A	HOH408
A	HOH455
A	HOH529
A	HOH530
A	HOH531
A	HOH554
A	HOH555
A	HOH565
A	HOH577

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Functional Information from PROSITE/UniProt

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIpsFMcQAG

Chain	Residue	Details
A	TYR90-GLY107

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
A	LYS67

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site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
A	LYS86
A	ILE175
A	LYS190

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
A	LYS167

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: S-nitrosocysteine => ECO:0000250|UniProtKB:Q99KR7

Chain	Residue	Details
A	CYS203

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