3RBA
Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis complexed with DPCoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0034214 | biological_process | protein hexamerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE COD A 3000 |
| Chain | Residue |
| A | GLY8 |
| A | ASN105 |
| A | THR118 |
| A | TYR122 |
| A | VAL125 |
| A | GLU132 |
| A | LEU136 |
| A | HOH161 |
| A | HOH172 |
| A | HOH189 |
| A | HOH200 |
| A | SER9 |
| A | HOH215 |
| A | HOH216 |
| A | PHE10 |
| A | HIS17 |
| A | LEU72 |
| A | VAL73 |
| A | LYS87 |
| A | GLY88 |
| A | GLU98 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:20851704, ECO:0007744|PDB:3NBK |
| Chain | Residue | Details |
| A | SER9 | |
| A | VAL73 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:23151631, ECO:0000305|PubMed:20851704, ECO:0007744|PDB:3NBA, ECO:0007744|PDB:3UC5 |
| Chain | Residue | Details |
| A | HIS17 | |
| A | GLY88 | |
| A | TYR122 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151 |
| Chain | Residue | Details |
| A | LYS41 | |
| A | LYS87 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:23151631, ECO:0007744|PDB:3UC5 |
| Chain | Residue | Details |
| A | GLU98 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20851704, ECO:0007744|PDB:3NBK |
| Chain | Residue | Details |
| A | ASN105 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23151631, ECO:0000305|PubMed:20851704, ECO:0007744|PDB:3NBA, ECO:0007744|PDB:3UC5 |
| Chain | Residue | Details |
| A | THR118 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 |
| Chain | Residue | Details |
| A | HIS17 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylthreonine => ECO:0007744|PubMed:21969609 |
| Chain | Residue | Details |
| A | THR2 |
