3RAQ

Dpo4 extension ternary complex with 3'-terminal primer C base opposite the 1-methylguanine (MG1) lesion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE DGT A 414

Chain	Residue
A	ASP7
A	ASP105
A	LYS159
A	CA415
A	CA416
A	HOH519
A	HOH522
A	HOH532
A	HOH537
A	HOH540
A	HOH598
A	PHE8
A	HOH606
A	HOH630
E	DC905
E	MG1906
A	TYR10
A	PHE11
A	TYR12
A	ALA44
A	THR45
A	TYR48
A	ARG51

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 415

Chain	Residue
A	ASP7
A	ASP105
A	GLU106
A	DGT414
A	CA416
A	HOH519
A	HOH538

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 416

Chain	Residue
A	ASP7
A	PHE8
A	ASP105
A	DGT414
A	CA415

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 417

Chain	Residue
A	ALA181
A	ILE186
A	HOH513
A	HOH515
A	HOH516
D	DG813

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE D 1

Chain	Residue
A	ALA102
A	SER103
A	ILE104
A	HOH537
D	HOH148
D	DG813
D	DOC814
E	DC907
E	DT908
E	DA909

---

site_id	AC6
Number of Residues	20
Details	BINDING SITE FOR RESIDUE DGT B 1414

Chain	Residue
B	HOH15
B	HOH31
B	HOH64
B	HOH261
B	ASP1007
B	PHE1008
B	TYR1010
B	PHE1011
B	TYR1012
B	ALA1044
B	THR1045
B	TYR1048
B	ARG1051
B	ASP1105
B	LYS1159
B	CA1415
B	CA1416
H	HOH122
J	DC1905
J	MG11906

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 1415

Chain	Residue
B	HOH60
B	ASP1007
B	ASP1105
B	GLU1106
B	DGT1414
B	HOH1519

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA B 1416

Chain	Residue
B	ASP1007
B	PHE1008
B	ASP1105
B	DGT1414

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 1417

Chain	Residue
B	ALA1181
B	ILE1186
B	HOH1514
B	HOH1515
B	HOH1516
H	DG1813

---

site_id	BC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE H 1001

Chain	Residue
B	HOH121
B	ALA1102
B	SER1103
B	ILE1104
H	HOH122
H	DG1813
H	DOC1814
J	DC1907
J	DT1908
J	DA1909

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE:

Chain	Residue	Details
A	GLU106
B	GLU1106

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	ASP7
A	ASP105
B	ASP1007
B	ASP1105

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Substrate discrimination

Chain	Residue	Details
A	TYR12
B	TYR1012

---