Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0004497 | molecular_function | monooxygenase activity |
B | 0005506 | molecular_function | iron ion binding |
B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
B | 0020037 | molecular_function | heme binding |
B | 0046872 | molecular_function | metal ion binding |
C | 0004497 | molecular_function | monooxygenase activity |
C | 0005506 | molecular_function | iron ion binding |
C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
C | 0020037 | molecular_function | heme binding |
C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE HEM A 501 |
Chain | Residue |
A | PHE97 |
A | LEU264 |
A | MET297 |
A | VAL303 |
A | ARG308 |
A | GLY358 |
A | PHE359 |
A | GLY360 |
A | ALA363 |
A | HIS364 |
A | CYS366 |
A | LEU98 |
A | GLY368 |
A | ALA372 |
A | D12509 |
A | HOH615 |
A | HOH696 |
A | HIS105 |
A | ARG109 |
A | ILE159 |
A | LEU252 |
A | LEU253 |
A | ALA256 |
A | THR260 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE PO4 A 502 |
Chain | Residue |
A | GLU235 |
A | THR242 |
A | GLU243 |
A | K507 |
A | HOH707 |
A | HOH828 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE PO4 A 503 |
Chain | Residue |
A | ARG109 |
A | SER113 |
A | NA506 |
A | HOH744 |
A | HOH834 |
B | ASN50 |
B | ARG81 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 504 |
Chain | Residue |
A | VAL341 |
A | GLY342 |
A | ARG351 |
A | GLN353 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 505 |
Chain | Residue |
A | ILE78 |
A | TYR309 |
A | THR326 |
A | HOH753 |
A | HOH775 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE NA A 506 |
Chain | Residue |
A | GLY110 |
A | SER113 |
A | PO4503 |
A | HOH835 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE K A 507 |
Chain | Residue |
A | GLU235 |
A | GLY238 |
A | LEU241 |
A | PO4502 |
A | HOH785 |
site_id | AC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO A 508 |
Chain | Residue |
A | ARG109 |
A | GLY362 |
A | ALA363 |
A | HOH835 |
B | PRO47 |
B | GLU48 |
B | ARG81 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE D12 A 509 |
Chain | Residue |
A | LEU252 |
A | ALA256 |
A | HEM501 |
site_id | BC1 |
Number of Residues | 25 |
Details | BINDING SITE FOR RESIDUE HEM B 501 |
Chain | Residue |
B | PHE97 |
B | LEU98 |
B | HIS105 |
B | ARG109 |
B | ILE159 |
B | LEU252 |
B | LEU253 |
B | ALA256 |
B | THR260 |
B | THR261 |
B | LEU264 |
B | MET297 |
B | VAL303 |
B | ARG308 |
B | GLY358 |
B | PHE359 |
B | GLY360 |
B | ALA363 |
B | HIS364 |
B | CYS366 |
B | GLY368 |
B | ALA372 |
B | D12509 |
B | HOH668 |
B | HOH669 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PO4 B 502 |
Chain | Residue |
B | GLU235 |
B | THR242 |
B | GLU243 |
B | K508 |
B | HOH741 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 503 |
Chain | Residue |
B | EDO506 |
B | VAL341 |
B | GLY342 |
B | ARG351 |
B | GLN353 |
site_id | BC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 504 |
Chain | Residue |
B | SER76 |
B | ILE78 |
B | TYR309 |
B | THR326 |
B | HOH646 |
B | HOH822 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 505 |
Chain | Residue |
B | ALA343 |
B | ARG346 |
C | ASP350 |
C | ARG351 |
C | ALA352 |
site_id | BC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 506 |
Chain | Residue |
B | GLY342 |
B | ARG346 |
B | ASP348 |
B | ARG351 |
B | EDO503 |
site_id | BC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 507 |
Chain | Residue |
B | SER56 |
B | ASP59 |
B | GLY317 |
B | HOH647 |
site_id | BC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE K B 508 |
Chain | Residue |
B | GLU235 |
B | GLY238 |
B | LEU241 |
B | PO4502 |
site_id | BC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE D12 B 509 |
Chain | Residue |
B | LEU98 |
B | LEU184 |
B | ASN251 |
B | HEM501 |
site_id | CC1 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE HEM C 501 |
Chain | Residue |
C | PHE97 |
C | LEU98 |
C | HIS105 |
C | ARG109 |
C | ILE159 |
C | LEU252 |
C | LEU253 |
C | ALA256 |
C | THR260 |
C | THR261 |
C | LEU264 |
C | MET297 |
C | VAL303 |
C | ARG308 |
C | GLY358 |
C | PHE359 |
C | GLY360 |
C | HIS364 |
C | CYS366 |
C | GLY368 |
C | ALA372 |
C | D12513 |
C | HOH642 |
C | HOH654 |
site_id | CC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PO4 C 502 |
Chain | Residue |
C | GLU235 |
C | THR242 |
C | GLU243 |
C | K512 |
C | HOH687 |
site_id | CC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE PO4 C 503 |
Chain | Residue |
B | ARG109 |
B | SER113 |
C | ASN50 |
C | ARG81 |
C | NA511 |
C | HOH614 |
C | HOH772 |
site_id | CC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO C 504 |
Chain | Residue |
C | ALA183 |
C | ASP185 |
C | PHE187 |
C | LEU188 |
C | HOH627 |
C | HOH656 |
C | HOH727 |
C | HOH757 |
site_id | CC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO C 505 |
Chain | Residue |
A | PRO47 |
A | GLU48 |
A | ARG81 |
C | ARG109 |
C | GLY362 |
C | ALA363 |
C | EDO508 |
C | HOH779 |
site_id | CC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO C 506 |
Chain | Residue |
C | VAL341 |
C | GLY342 |
C | ARG351 |
C | GLN353 |
site_id | CC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 507 |
Chain | Residue |
B | ARG109 |
B | ALA363 |
B | HOH602 |
C | PRO47 |
C | GLU48 |
C | ARG81 |
site_id | CC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 508 |
Chain | Residue |
C | ARG109 |
C | GLY110 |
C | SER113 |
C | EDO505 |
C | HOH779 |
C | HOH819 |
site_id | CC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 509 |
Chain | Residue |
C | SER76 |
C | PHE79 |
C | TYR309 |
C | THR326 |
C | HOH727 |
C | HOH790 |
site_id | DC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO C 510 |
Chain | Residue |
C | SER56 |
C | ASP59 |
C | GLY317 |
C | HOH641 |
site_id | DC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA C 511 |
Chain | Residue |
B | GLY110 |
B | SER113 |
B | HOH602 |
C | PO4503 |
C | HOH825 |
site_id | DC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE K C 512 |
Chain | Residue |
C | GLU235 |
C | GLY238 |
C | LEU241 |
C | PO4502 |
C | HOH648 |
site_id | DC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE D12 C 513 |
Chain | Residue |
C | LEU184 |
C | LEU252 |
C | ILE255 |
C | ALA256 |
C | HEM501 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGkGAHFCLG |
Chain | Residue | Details |
A | PHE359-GLY368 | |