3R93
Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide
Functional Information from PROSITE/UniProt
| site_id | PS00598 |
| Number of Residues | 21 |
| Details | CHROMO_1 Chromo domain signature. YkVRWkGYtsddd.TWEPeihL |
| Chain | Residue | Details |
| A | TYR76-LEU96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| E | ARG2 | |
| F | ARG2 | |
| G | ARG2 | |
| H | ARG2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| E | THR3 | |
| F | THR3 | |
| G | THR3 | |
| H | THR3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | LYS4 | |
| F | LYS4 | |
| G | LYS4 | |
| H | LYS4 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| E | GLN5 | |
| F | GLN5 | |
| G | GLN5 | |
| H | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790 |
| Chain | Residue | Details |
| E | THR6 | |
| F | THR6 | |
| G | THR6 | |
| H | THR6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P84228 |
| Chain | Residue | Details |
| E | ARG8 | |
| F | ARG8 | |
| G | ARG8 | |
| H | ARG8 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | M3L9 | |
| F | M3L9 | |
| G | M3L9 | |
| H | M3L9 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| E | SER10 | |
| F | SER10 | |
| G | SER10 | |
| H | SER10 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:18066052, ECO:0000269|PubMed:22901803 |
| Chain | Residue | Details |
| E | THR11 | |
| F | THR11 | |
| G | THR11 | |
| H | THR11 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| E | LYS14 | |
| F | LYS14 | |
| G | LYS14 | |
| H | LYS14 |
