3R8B
Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090729 | molecular_function | toxin activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0035821 | biological_process | modulation of process of another organism |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0090729 | molecular_function | toxin activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0035821 | biological_process | modulation of process of another organism |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0090729 | molecular_function | toxin activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0005576 | cellular_component | extracellular region |
| G | 0035821 | biological_process | modulation of process of another organism |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0090729 | molecular_function | toxin activity |
| I | 0005515 | molecular_function | protein binding |
| I | 0005576 | cellular_component | extracellular region |
| I | 0035821 | biological_process | modulation of process of another organism |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0090729 | molecular_function | toxin activity |
| K | 0005515 | molecular_function | protein binding |
| K | 0005576 | cellular_component | extracellular region |
| K | 0035821 | biological_process | modulation of process of another organism |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0090729 | molecular_function | toxin activity |
| M | 0005515 | molecular_function | protein binding |
| M | 0005576 | cellular_component | extracellular region |
| M | 0035821 | biological_process | modulation of process of another organism |
| M | 0046872 | molecular_function | metal ion binding |
| M | 0090729 | molecular_function | toxin activity |
| O | 0005515 | molecular_function | protein binding |
| O | 0005576 | cellular_component | extracellular region |
| O | 0035821 | biological_process | modulation of process of another organism |
| O | 0046872 | molecular_function | metal ion binding |
| O | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN B 121 |
| Chain | Residue |
| B | GLU42 |
| B | ARG44 |
| D | ASP59 |
| D | CL123 |
| D | CL124 |
| F | ASP59 |
| P | ZN121 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN P 121 |
| Chain | Residue |
| D | CL123 |
| D | CL124 |
| F | ASP59 |
| P | GLU42 |
| P | ARG44 |
| B | ZN121 |
| D | ASP59 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN F 121 |
| Chain | Residue |
| B | ASP59 |
| B | CL123 |
| B | CL124 |
| D | ZN121 |
| F | GLU42 |
| F | ARG44 |
| P | ASP59 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN D 121 |
| Chain | Residue |
| B | ASP59 |
| B | CL123 |
| B | CL124 |
| D | GLU42 |
| D | ARG44 |
| F | ZN121 |
| P | ASP59 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 122 |
| Chain | Residue |
| B | MET48 |
| B | HIS50 |
| B | GLU56 |
| D | HIS41 |
| O | ASP206 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 122 |
| Chain | Residue |
| B | HIS41 |
| D | MET48 |
| D | HIS50 |
| D | GLU56 |
| E | ASP206 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN J 121 |
| Chain | Residue |
| G | ASP206 |
| J | MET48 |
| J | HIS50 |
| J | GLU56 |
| N | HIS41 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN F 122 |
| Chain | Residue |
| C | ASP206 |
| F | MET48 |
| F | HIS50 |
| F | GLU56 |
| P | HIS41 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN L 121 |
| Chain | Residue |
| H | HIS41 |
| L | MET48 |
| L | HIS50 |
| L | GLU56 |
| M | ASP206 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN H 121 |
| Chain | Residue |
| H | MET48 |
| H | HIS50 |
| H | GLU56 |
| I | ASP206 |
| L | HIS41 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN P 122 |
| Chain | Residue |
| A | ASP206 |
| F | HIS41 |
| P | MET48 |
| P | HIS50 |
| P | GLU56 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN J 122 |
| Chain | Residue |
| H | ASP59 |
| H | ZN122 |
| J | ASP59 |
| J | CL123 |
| J | CL124 |
| N | GLU42 |
| N | ARG44 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN H 122 |
| Chain | Residue |
| H | ASP59 |
| J | ZN122 |
| J | CL123 |
| J | CL124 |
| L | GLU42 |
| L | ARG44 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN N 121 |
| Chain | Residue |
| J | GLU42 |
| J | ARG44 |
| L | ASP59 |
| L | ZN122 |
| L | CL123 |
| N | ASP59 |
| N | CL123 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN N 122 |
| Chain | Residue |
| J | HIS41 |
| K | ASP206 |
| N | MET48 |
| N | HIS50 |
| N | GLU56 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN L 122 |
| Chain | Residue |
| H | GLU42 |
| H | ARG44 |
| L | ASP59 |
| L | CL123 |
| N | ASP59 |
| N | ZN121 |
| N | CL123 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN C 240 |
| Chain | Residue |
| C | HIS121 |
| M | LYS239 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN G 240 |
| Chain | Residue |
| G | HIS121 |
| O | LYS239 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN E 240 |
| Chain | Residue |
| E | HIS121 |
| J | GLU1 |
| site_id | CC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN K 240 |
| Chain | Residue |
| K | HIS121 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN M 241 |
| Chain | Residue |
| M | HIS121 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN O 241 |
| Chain | Residue |
| O | HIS121 |
| site_id | CC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN I 240 |
| Chain | Residue |
| I | HIS121 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN I 241 |
| Chain | Residue |
| A | HIS121 |
| I | LYS239 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL J 123 |
| Chain | Residue |
| H | ASP59 |
| H | ZN122 |
| J | ASP59 |
| J | ZN122 |
| L | GLU42 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 123 |
| Chain | Residue |
| B | GLU42 |
| B | ZN121 |
| D | ASP59 |
| F | ASP59 |
| P | ZN121 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 123 |
| Chain | Residue |
| B | ASP59 |
| D | ZN121 |
| F | GLU42 |
| F | ZN121 |
| P | ASP59 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL J 124 |
| Chain | Residue |
| H | ASP59 |
| H | ZN122 |
| J | ASP59 |
| J | ZN122 |
| N | ARG44 |
| N | CL123 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 124 |
| Chain | Residue |
| B | ZN121 |
| B | CL124 |
| D | ASP59 |
| F | ASP59 |
| P | ZN121 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL L 123 |
| Chain | Residue |
| J | GLU42 |
| L | ASP59 |
| L | ZN122 |
| N | ASP59 |
| N | ZN121 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 124 |
| Chain | Residue |
| B | ASP59 |
| D | ZN121 |
| D | CL124 |
| F | ZN121 |
| P | ASP59 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL N 123 |
| Chain | Residue |
| J | CL124 |
| L | ASP59 |
| L | ZN122 |
| N | ASP59 |
| N | ZN121 |
| site_id | DC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL I 242 |
| Chain | Residue |
| I | LEU20 |
| I | ASN23 |
| I | LYS207 |
| I | PHE208 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 240 |
| Chain | Residue |
| A | LEU20 |
| A | ASN23 |
| A | LYS207 |
| A | PHE208 |
| site_id | DC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL G 241 |
| Chain | Residue |
| G | LEU20 |
| G | ASN23 |
| G | LYS207 |
| G | PHE208 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 241 |
| Chain | Residue |
| C | LEU20 |
| C | ASN23 |
| C | PHE208 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL M 242 |
| Chain | Residue |
| M | LEU20 |
| M | ASN23 |
| M | PHE208 |
| site_id | EC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL O 242 |
| Chain | Residue |
| O | LEU20 |
| O | ASN23 |
| O | PHE208 |
| site_id | EC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 241 |
| Chain | Residue |
| A | GLN125 |
| A | ASP127 |
Functional Information from PROSITE/UniProt
| site_id | PS00277 |
| Number of Residues | 10 |
| Details | STAPH_STREP_TOXIN_1 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. YGGVTEHngN |
| Chain | Residue | Details |
| A | TYR115-ASN124 |
| site_id | PS00278 |
| Number of Residues | 24 |
| Details | STAPH_STREP_TOXIN_2 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. KkkVtaqeLDyltRhyLvknkkLY |
| Chain | Residue | Details |
| A | LYS152-TYR175 |
