3R7L
Crystal Structure of PALA-bound Aspartate Transcarbamoylase from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| C | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| C | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| D | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| D | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0016597 | molecular_function | amino acid binding |
| D | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| D | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| E | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| E | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| E | 0006520 | biological_process | amino acid metabolic process |
| E | 0016597 | molecular_function | amino acid binding |
| E | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| E | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| F | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| F | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| F | 0006520 | biological_process | amino acid metabolic process |
| F | 0016597 | molecular_function | amino acid binding |
| F | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| F | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PAL A 311 |
| Chain | Residue |
| A | SER47 |
| A | ALA250 |
| A | HOH331 |
| A | HOH341 |
| A | HOH343 |
| B | SER74 |
| B | LYS77 |
| A | THR48 |
| A | ARG49 |
| A | THR50 |
| A | ARG99 |
| A | HIS127 |
| A | ARG160 |
| A | ARG211 |
| A | GLN213 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PAL B 312 |
| Chain | Residue |
| B | SER47 |
| B | THR48 |
| B | ARG49 |
| B | THR50 |
| B | ARG99 |
| B | HIS127 |
| B | ARG160 |
| B | ARG211 |
| B | GLN213 |
| B | ALA250 |
| B | HOH310 |
| B | HOH326 |
| B | HOH341 |
| C | SER74 |
| C | LYS77 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 C 305 |
| Chain | Residue |
| A | LYS59 |
| B | LYS59 |
| B | HOH305 |
| C | LYS59 |
| C | HOH311 |
| C | HOH332 |
| C | HOH425 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PAL C 313 |
| Chain | Residue |
| A | SER74 |
| A | LYS77 |
| C | SER47 |
| C | THR48 |
| C | ARG49 |
| C | THR50 |
| C | ARG99 |
| C | HIS127 |
| C | ARG160 |
| C | ARG211 |
| C | GLN213 |
| C | ALA250 |
| C | HOH309 |
| C | HOH323 |
| C | HOH342 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 D 305 |
| Chain | Residue |
| D | LYS59 |
| D | HOH476 |
| D | HOH493 |
| E | LYS59 |
| F | LYS59 |
| F | HOH308 |
| F | HOH320 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PAL D 314 |
| Chain | Residue |
| D | SER47 |
| D | THR48 |
| D | ARG49 |
| D | THR50 |
| D | ARG99 |
| D | HIS127 |
| D | GLN130 |
| D | ARG160 |
| D | ARG211 |
| D | GLN213 |
| D | ALA250 |
| D | HOH311 |
| D | HOH313 |
| D | HOH317 |
| E | SER74 |
| E | LYS77 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PAL E 315 |
| Chain | Residue |
| E | SER47 |
| E | THR48 |
| E | ARG49 |
| E | THR50 |
| E | ARG99 |
| E | HIS127 |
| E | ARG160 |
| E | ARG211 |
| E | GLN213 |
| E | ALA250 |
| E | HOH318 |
| E | HOH320 |
| E | HOH387 |
| F | SER74 |
| F | LYS77 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PAL F 316 |
| Chain | Residue |
| F | ARG211 |
| F | GLN213 |
| F | ALA250 |
| F | HOH315 |
| F | HOH326 |
| F | HOH568 |
| D | SER74 |
| D | LYS77 |
| F | SER47 |
| F | THR48 |
| F | ARG49 |
| F | THR50 |
| F | ARG99 |
| F | HIS127 |
| F | ARG160 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FfEpSTRT |
| Chain | Residue | Details |
| A | PHE43-THR50 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 60 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00001","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
