3R7D

Crystal Structure of Unliganded Aspartate Transcarbamoylase from Bacillus subtilis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004070	molecular_function	aspartate carbamoyltransferase activity
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006520	biological_process	amino acid metabolic process
A	0016597	molecular_function	amino acid binding
A	0016740	molecular_function	transferase activity
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
A	0044205	biological_process	'de novo' UMP biosynthetic process
B	0004070	molecular_function	aspartate carbamoyltransferase activity
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006520	biological_process	amino acid metabolic process
B	0016597	molecular_function	amino acid binding
B	0016740	molecular_function	transferase activity
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0044205	biological_process	'de novo' UMP biosynthetic process
C	0004070	molecular_function	aspartate carbamoyltransferase activity
C	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006520	biological_process	amino acid metabolic process
C	0016597	molecular_function	amino acid binding
C	0016740	molecular_function	transferase activity
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0044205	biological_process	'de novo' UMP biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PO4 A 305

Chain	Residue
A	ASN67
B	ASN67
B	HOH313
C	ASN67
A	HOH319
A	HOH323
A	HOH328
A	HOH334
A	HOH367
A	HOH385
A	HOH388
A	HOH411

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 A 306

Chain	Residue
A	SER11
A	THR12
A	ARG171
A	HOH312
A	HOH343

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 307

Chain	Residue
A	THR73
A	SER74
A	LYS77
C	SER47
C	THR48
C	ARG49
C	PRO251

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 B 305

Chain	Residue
B	SER11
B	THR12
B	ARG171
B	HOH372
B	HOH484

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 C 305

Chain	Residue
C	LYS272
C	LYS275
C	HOH357
C	HOH381

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 C 306

Chain	Residue
C	SER11
C	THR12
C	ARG171
C	HOH359
C	HOH573

---

Functional Information from PROSITE/UniProt

site_id	PS00097
Number of Residues	8
Details	CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FfEpSTRT

Chain	Residue	Details
A	PHE43-THR50

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00001

Chain	Residue	Details
A	ARG49
A	PRO251
B	ARG49
B	THR50
B	LYS77
B	ARG99
B	HIS127
B	GLN130
B	ARG160
B	ARG211
B	ALA250
A	THR50
B	PRO251
C	ARG49
C	THR50
C	LYS77
C	ARG99
C	HIS127
C	GLN130
C	ARG160
C	ARG211
C	ALA250
A	LYS77
C	PRO251
A	ARG99
A	HIS127
A	GLN130
A	ARG160
A	ARG211
A	ALA250

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:17218307

Chain	Residue	Details
A	SER303
B	SER303
C	SER303

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