3R6E
The structure of Thermococcus thioreducens' inorganic pyrophosphatase bound to sulfate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006796 | biological_process | phosphate-containing compound metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006796 | biological_process | phosphate-containing compound metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006796 | biological_process | phosphate-containing compound metabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006796 | biological_process | phosphate-containing compound metabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1855 |
| Chain | Residue |
| A | ARG44 |
| A | LYS141 |
| A | LYS146 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1863 |
| Chain | Residue |
| A | HOH1537 |
| A | HOH1538 |
| A | HOH1539 |
| A | HOH1540 |
| A | LYS30 |
| A | TYR56 |
| A | ASP103 |
| A | TYR140 |
| A | LYS141 |
| A | HOH1293 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1856 |
| Chain | Residue |
| B | ARG44 |
| B | LYS141 |
| B | LYS146 |
| B | HOH663 |
| B | HOH905 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1857 |
| Chain | Residue |
| B | MSE96 |
| B | ASP103 |
| B | LYS105 |
| B | LYS141 |
| B | HOH792 |
| B | HOH833 |
| B | HOH905 |
| B | HOH1151 |
| B | HOH1152 |
| B | HOH1207 |
| B | HOH1317 |
| B | HOH1566 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1860 |
| Chain | Residue |
| C | ARG44 |
| C | LYS141 |
| C | LYS146 |
| C | HOH1123 |
| C | HOH1241 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1858 |
| Chain | Residue |
| D | ARG44 |
| D | LYS141 |
| D | LYS146 |
| D | HOH1270 |
| D | HOH1403 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1862 |
| Chain | Residue |
| D | LYS30 |
| D | TYR56 |
| D | ASP71 |
| D | HOH204 |
| D | HOH496 |
| D | HOH856 |
| D | HOH1228 |
| D | HOH1571 |
| D | NH41864 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NH4 D 1864 |
| Chain | Residue |
| D | HOH333 |
| D | HOH599 |
| D | HOH1571 |
| D | HOH1764 |
| D | SO41862 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 E 1854 |
| Chain | Residue |
| E | LYS30 |
| E | TYR56 |
| E | ASP71 |
| E | MSE96 |
| E | ASP103 |
| E | LYS105 |
| E | LYS141 |
| E | HOH199 |
| E | HOH258 |
| E | HOH426 |
| E | HOH1062 |
| E | HOH1579 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 1859 |
| Chain | Residue |
| E | ARG44 |
| E | LYS141 |
| E | LYS146 |
| E | HOH1282 |
| E | HOH1388 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 F 1861 |
| Chain | Residue |
| F | ARG44 |
| F | LYS141 |
| F | LYS146 |
| F | HOH546 |
| F | HOH1435 |
Functional Information from PROSITE/UniProt
| site_id | PS00387 |
| Number of Residues | 7 |
| Details | PPASE Inorganic pyrophosphatase signature. DGDPFDI |
| Chain | Residue | Details |
| A | ASP66-ILE72 |
