3R5V

The structure of calcium bound Thermococcus thioreducens inorganic pyrophosphatase at 298K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004427	molecular_function	inorganic diphosphate phosphatase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006796	biological_process	phosphate-containing compound metabolic process
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004427	molecular_function	inorganic diphosphate phosphatase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006796	biological_process	phosphate-containing compound metabolic process
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004427	molecular_function	inorganic diphosphate phosphatase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006796	biological_process	phosphate-containing compound metabolic process
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004427	molecular_function	inorganic diphosphate phosphatase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006796	biological_process	phosphate-containing compound metabolic process
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0004427	molecular_function	inorganic diphosphate phosphatase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006796	biological_process	phosphate-containing compound metabolic process
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0004427	molecular_function	inorganic diphosphate phosphatase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006796	biological_process	phosphate-containing compound metabolic process
F	0016787	molecular_function	hydrolase activity
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 201

Chain	Residue
A	ASP66
A	ASP71
A	ASP103
A	HOH312
A	HOH323
A	HOH337

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 201

Chain	Residue
B	HOH309
B	HOH333
B	HOH371
B	ASP66
B	ASP71
B	ASP103

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MRD C 201

Chain	Residue
C	ARG77
C	TYR115
C	HOH364
C	HOH365
E	TYR115
E	HOH332

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPD C 202

Chain	Residue
C	TYR115
E	HOH311
E	HOH369
E	HOH375

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 203

Chain	Residue
C	ASP66
C	ASP71
C	ASP103
C	HOH318
C	HOH345
C	HOH378

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 201

Chain	Residue
D	ASP66
D	ASP71
D	ASP103
D	HOH325
D	HOH360
D	HOH380

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA E 201

Chain	Residue
E	ASP66
E	ASP71
E	ASP103
E	HOH321
E	HOH344
E	HOH373

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA F 201

Chain	Residue
F	ASP66
F	ASP71
F	ASP103
F	HOH327
F	HOH340
F	HOH353

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MRD F 202

Chain	Residue
D	TYR115
D	PHE116
D	HOH356
F	TYR115
F	HOH383
F	HOH384

---

Functional Information from PROSITE/UniProt

site_id	PS00387
Number of Residues	7
Details	PPASE Inorganic pyrophosphatase signature. DGDPFDI

Chain	Residue	Details
A	ASP66-ILE72

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