Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008234 | molecular_function | cysteine-type peptidase activity |
C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
C | 0008234 | molecular_function | cysteine-type peptidase activity |
D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
D | 0006508 | biological_process | proteolysis |
D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR CHAIN E OF PEPTIDE (ACE)ADVAD-CHO |
Chain | Residue |
A | ARG219 |
B | THR380 |
B | TRP385 |
B | GLY419 |
B | TYR420 |
B | ALA421 |
B | PHE426 |
A | HIS277 |
A | GLY278 |
A | GLN318 |
A | CYS320 |
B | ALA376 |
B | MET377 |
B | ARG378 |
B | ASN379 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR CHAIN F OF PEPTIDE (ACE)ADVAD-CHO |
Chain | Residue |
B | ASP416 |
C | ARG219 |
C | HIS277 |
C | GLY278 |
C | GLN318 |
C | CYS320 |
D | ALA376 |
D | MET377 |
D | ARG378 |
D | ASN379 |
D | THR380 |
D | LYS381 |
D | TRP385 |
D | GLY419 |
D | TYR420 |
D | ALA421 |
D | PHE426 |
Functional Information from PROSITE/UniProt
site_id | PS01121 |
Number of Residues | 15 |
Details | CASPASE_HIS Caspase family histidine active site. HrvtdSciVaLLSHG |
Chain | Residue | Details |
A | HIS264-GLY278 | |
site_id | PS01122 |
Number of Residues | 12 |
Details | CASPASE_CYS Caspase family cysteine active site. KPKMFFIQACRG |
Chain | Residue | Details |
A | LYS311-GLY322 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: ACT_SITE => ECO:0000250 |
Chain | Residue | Details |
A | HIS277 | |
A | CYS320 | |
C | HIS277 | |
C | CYS320 | |