3R5C

Pseudomonas aeruginosa DapD (PA3666) in complex with CoA and succinate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
A	0009085	biological_process	lysine biosynthetic process
A	0009089	biological_process	lysine biosynthetic process via diaminopimelate
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0019877	biological_process	diaminopimelate biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0008652	biological_process	amino acid biosynthetic process
B	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
B	0009085	biological_process	lysine biosynthetic process
B	0009089	biological_process	lysine biosynthetic process via diaminopimelate
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0019877	biological_process	diaminopimelate biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0008652	biological_process	amino acid biosynthetic process
C	0008666	molecular_function	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity
C	0009085	biological_process	lysine biosynthetic process
C	0009089	biological_process	lysine biosynthetic process via diaminopimelate
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0019877	biological_process	diaminopimelate biosynthetic process
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE COA A 351

Chain	Residue
A	THR285
C	ARG317
C	ARG318
C	ASN319
C	SER320
A	GLY287
A	LYS289
A	LYS304
A	SIN352
C	GLY263
C	ALA264
C	GLU279
C	ALA280

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SIN A 352

Chain	Residue
A	ARG223
A	SER225
A	SER241
A	THR242
A	COA351
C	GLU221
C	GLY237
C	GLY238
C	ALA264
C	HOH357

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SIN A 345

Chain	Residue
A	GLU221
A	GLY237
A	GLY238
A	ALA264
B	ARG223
B	SER225
B	SER241
B	THR242

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE COA B 351

Chain	Residue
A	GLY263
A	ALA264
A	GLU279
A	ALA280
A	ARG317
A	ARG318
A	ASN319
A	SER320
B	MET243
B	GLY287
B	LYS289
B	LYS304

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE COA C 351

Chain	Residue
B	GLY263
B	ALA264
B	ILE277
B	GLU279
B	ALA280
B	ARG317
B	ARG318
B	ASN319
B	SER320
B	HOH380
C	GLN59
C	GLN63
C	MET243
C	THR285
C	GLY287
C	LYS289
C	LYS304
C	SIN352

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SIN C 352

Chain	Residue
B	GLU221
B	GLY238
C	ARG223
C	SER225
C	SER241
C	THR242
C	COA351
C	HOH375

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"Acyl-anhydride intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_02122","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02122","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	33
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22359568","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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