3R4I
Crystal structure of a Citrate lyase (Bxe_B2899) from BURKHOLDERIA XENOVORANS LB400 at 2.24 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008815 | molecular_function | citrate (pro-3S)-lyase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047777 | molecular_function | (S)-citramalyl-CoA lyase activity |
| A | 0106064 | biological_process | regulation of cobalamin metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008815 | molecular_function | citrate (pro-3S)-lyase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047777 | molecular_function | (S)-citramalyl-CoA lyase activity |
| B | 0106064 | biological_process | regulation of cobalamin metabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008815 | molecular_function | citrate (pro-3S)-lyase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047777 | molecular_function | (S)-citramalyl-CoA lyase activity |
| C | 0106064 | biological_process | regulation of cobalamin metabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008815 | molecular_function | citrate (pro-3S)-lyase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047777 | molecular_function | (S)-citramalyl-CoA lyase activity |
| D | 0106064 | biological_process | regulation of cobalamin metabolic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0008815 | molecular_function | citrate (pro-3S)-lyase activity |
| E | 0016829 | molecular_function | lyase activity |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0047777 | molecular_function | (S)-citramalyl-CoA lyase activity |
| E | 0106064 | biological_process | regulation of cobalamin metabolic process |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0008815 | molecular_function | citrate (pro-3S)-lyase activity |
| F | 0016829 | molecular_function | lyase activity |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0047777 | molecular_function | (S)-citramalyl-CoA lyase activity |
| F | 0106064 | biological_process | regulation of cobalamin metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 341 |
| Chain | Residue |
| A | GLU151 |
| A | ASP177 |
| A | HOH372 |
| A | HOH381 |
| A | HOH427 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 346 |
| Chain | Residue |
| B | HOH408 |
| A | ASP230 |
| A | HOH390 |
| A | HOH391 |
| A | HOH550 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 339 |
| Chain | Residue |
| B | GLU151 |
| B | ASP177 |
| B | CL354 |
| B | HOH395 |
| B | HOH397 |
| B | HOH432 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 340 |
| Chain | Residue |
| A | HOH385 |
| A | HOH561 |
| B | ASP230 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 354 |
| Chain | Residue |
| B | GLY174 |
| B | LEU175 |
| B | MSE176 |
| B | ASP177 |
| B | CA339 |
| B | HOH483 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 343 |
| Chain | Residue |
| C | ARG86 |
| C | GLU151 |
| C | ASP177 |
| C | CL353 |
| C | HOH407 |
| C | HOH442 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 344 |
| Chain | Residue |
| C | ASP230 |
| C | HOH402 |
| C | HOH426 |
| D | HOH388 |
| D | HOH409 |
| D | HOH439 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C 353 |
| Chain | Residue |
| C | GLY174 |
| C | LEU175 |
| C | MSE176 |
| C | ASP177 |
| C | ALA300 |
| C | CA343 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT C 357 |
| Chain | Residue |
| C | ARG86 |
| C | MSE176 |
| C | TRP251 |
| C | ILE253 |
| C | ASP298 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 342 |
| Chain | Residue |
| D | GLU151 |
| D | ASP177 |
| D | CL352 |
| D | HOH364 |
| D | HOH430 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 345 |
| Chain | Residue |
| C | HOH382 |
| C | HOH404 |
| C | HOH446 |
| D | ASP230 |
| D | HOH549 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA D 350 |
| Chain | Residue |
| C | ASP91 |
| C | HIS120 |
| D | GLU126 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 352 |
| Chain | Residue |
| D | GLY174 |
| D | MSE176 |
| D | ASP177 |
| D | ALA300 |
| D | CA342 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT D 358 |
| Chain | Residue |
| D | ARG86 |
| D | MSE176 |
| D | TRP251 |
| D | ASP298 |
| D | HOH364 |
| D | HOH430 |
| D | HOH433 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA E 347 |
| Chain | Residue |
| E | ASP230 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA E 348 |
| Chain | Residue |
| E | GLU151 |
| E | ASP177 |
| E | CL355 |
| E | HOH463 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL E 355 |
| Chain | Residue |
| E | GLY174 |
| E | LEU175 |
| E | MSE176 |
| E | ASP177 |
| E | CA348 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA F 349 |
| Chain | Residue |
| F | ARG86 |
| F | GLU151 |
| F | ASP177 |
| F | CL356 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA F 351 |
| Chain | Residue |
| E | HOH558 |
| F | ASP230 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL F 356 |
| Chain | Residue |
| F | GLY174 |
| F | MSE176 |
| F | ASP177 |
| F | ALA300 |
| F | CA349 |
