3R3V

Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Fluoroacetate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016787	molecular_function	hydrolase activity
A	0018785	molecular_function	haloacetate dehalogenase activity
B	0003824	molecular_function	catalytic activity
B	0016787	molecular_function	hydrolase activity
B	0018785	molecular_function	haloacetate dehalogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FAH A 305

Chain	Residue
A	ASN110
A	ARG111
A	ARG114
A	HIS155
A	TRP156
A	TYR219

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 306

Chain	Residue
A	GLN98
A	HOH367
B	HOH459

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 307

Chain	Residue
A	ARG114
A	LEU136
A	HOH477

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 308

Chain	Residue
A	ALA286
A	PRO287
A	ASP288
A	GLN289

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL B 305

Chain	Residue
B	ARG114
B	ILE135
B	LEU136
B	TYR141
B	HOH448

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 306

Chain	Residue
B	ASN110
B	ARG111
B	ARG114

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3R3V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Important for enzyme activity","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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