3R2N

Crystal structure of cytidine deaminase from Mycobacterium leprae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004126	molecular_function	cytidine deaminase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0009972	biological_process	cytidine deamination
A	0016787	molecular_function	hydrolase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0055086	biological_process	nucleobase-containing small molecule metabolic process
A	0072527	biological_process	pyrimidine-containing compound metabolic process
A	1901135	biological_process	carbohydrate derivative metabolic process
B	0003824	molecular_function	catalytic activity
B	0004126	molecular_function	cytidine deaminase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008270	molecular_function	zinc ion binding
B	0009972	biological_process	cytidine deamination
B	0016787	molecular_function	hydrolase activity
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0055086	biological_process	nucleobase-containing small molecule metabolic process
B	0072527	biological_process	pyrimidine-containing compound metabolic process
B	1901135	biological_process	carbohydrate derivative metabolic process
C	0003824	molecular_function	catalytic activity
C	0004126	molecular_function	cytidine deaminase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008270	molecular_function	zinc ion binding
C	0009972	biological_process	cytidine deamination
C	0016787	molecular_function	hydrolase activity
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0055086	biological_process	nucleobase-containing small molecule metabolic process
C	0072527	biological_process	pyrimidine-containing compound metabolic process
C	1901135	biological_process	carbohydrate derivative metabolic process
D	0003824	molecular_function	catalytic activity
D	0004126	molecular_function	cytidine deaminase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008270	molecular_function	zinc ion binding
D	0009972	biological_process	cytidine deamination
D	0016787	molecular_function	hydrolase activity
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0055086	biological_process	nucleobase-containing small molecule metabolic process
D	0072527	biological_process	pyrimidine-containing compound metabolic process
D	1901135	biological_process	carbohydrate derivative metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 135

Chain	Residue
A	CYS56
A	CYS89
A	CYS92
A	EDO136

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 136

Chain	Residue
A	HOH149
A	GLU58
A	LEU86
A	PRO88
A	CYS89
A	ZN135

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 135

Chain	Residue
B	CYS56
B	CYS89
B	CYS92
B	EDO136

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EDO B 136

Chain	Residue
B	VAL29
B	CYS56
B	GLU58
B	CYS78
B	MET87
B	PRO88
B	CYS89
B	CYS92
B	ZN135
B	HOH143

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 135

Chain	Residue
C	CYS56
C	CYS89
C	CYS92
C	EDO136

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO C 136

Chain	Residue
C	GLU58
C	PRO88
C	CYS89
C	ZN135
C	HOH138

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 135

Chain	Residue
D	CYS56
D	CYS89
D	CYS92
D	EDO136

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO D 136

Chain	Residue
D	GLU58
D	CYS78
D	MET87
D	PRO88
D	CYS89
D	CYS92
D	ZN135

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL D 137

Chain	Residue
D	ASP3
D	ASN5
D	PHE34

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Functional Information from PROSITE/UniProt

site_id	PS00903
Number of Residues	41
Details	CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. CAEcsMIsalyatgggrlvavycvdgngdslm........PCgr......CrqlL

Chain	Residue	Details
A	CYS56-LEU96

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