3R0Q

A Uniquely Open Conformation Revealed in the Crystal Structure of Arabidopsis Thaliana Protein Arginine Methyltransferase 10

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0006338	biological_process	chromatin remodeling
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008168	molecular_function	methyltransferase activity
A	0010228	biological_process	vegetative to reproductive phase transition of meristem
A	0016274	molecular_function	protein-arginine N-methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0018216	biological_process	peptidyl-arginine methylation
A	0019919	biological_process	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
A	0032259	biological_process	methylation
A	0035241	molecular_function	protein-arginine omega-N monomethyltransferase activity
A	0035242	molecular_function	protein-arginine omega-N asymmetric methyltransferase activity
A	0042054	molecular_function	histone methyltransferase activity
A	0044020	molecular_function	histone H4R3 methyltransferase activity
C	0005634	cellular_component	nucleus
C	0006338	biological_process	chromatin remodeling
C	0006355	biological_process	regulation of DNA-templated transcription
C	0008168	molecular_function	methyltransferase activity
C	0010228	biological_process	vegetative to reproductive phase transition of meristem
C	0016274	molecular_function	protein-arginine N-methyltransferase activity
C	0016740	molecular_function	transferase activity
C	0018216	biological_process	peptidyl-arginine methylation
C	0019919	biological_process	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
C	0032259	biological_process	methylation
C	0035241	molecular_function	protein-arginine omega-N monomethyltransferase activity
C	0035242	molecular_function	protein-arginine omega-N asymmetric methyltransferase activity
C	0042054	molecular_function	histone methyltransferase activity
C	0044020	molecular_function	histone H4R3 methyltransferase activity
E	0005634	cellular_component	nucleus
E	0006338	biological_process	chromatin remodeling
E	0006355	biological_process	regulation of DNA-templated transcription
E	0008168	molecular_function	methyltransferase activity
E	0010228	biological_process	vegetative to reproductive phase transition of meristem
E	0016274	molecular_function	protein-arginine N-methyltransferase activity
E	0016740	molecular_function	transferase activity
E	0018216	biological_process	peptidyl-arginine methylation
E	0019919	biological_process	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
E	0032259	biological_process	methylation
E	0035241	molecular_function	protein-arginine omega-N monomethyltransferase activity
E	0035242	molecular_function	protein-arginine omega-N asymmetric methyltransferase activity
E	0042054	molecular_function	histone methyltransferase activity
E	0044020	molecular_function	histone H4R3 methyltransferase activity
G	0005634	cellular_component	nucleus
G	0006338	biological_process	chromatin remodeling
G	0006355	biological_process	regulation of DNA-templated transcription
G	0008168	molecular_function	methyltransferase activity
G	0010228	biological_process	vegetative to reproductive phase transition of meristem
G	0016274	molecular_function	protein-arginine N-methyltransferase activity
G	0016740	molecular_function	transferase activity
G	0018216	biological_process	peptidyl-arginine methylation
G	0019919	biological_process	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
G	0032259	biological_process	methylation
G	0035241	molecular_function	protein-arginine omega-N monomethyltransferase activity
G	0035242	molecular_function	protein-arginine omega-N asymmetric methyltransferase activity
G	0042054	molecular_function	histone methyltransferase activity
G	0044020	molecular_function	histone H4R3 methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE SAH C 1

Chain	Residue
C	TYR39
C	ALA101
C	THR102
C	GLY126
C	SER127
C	VAL128
C	GLU129
C	GLU143
C	MET154
C	SER157
C	HOH396
C	GLN45
C	HOH404
C	MET48
C	ARG54
C	GLY78
C	THR79
C	ILE83
C	LEU84
C	GLU100

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAH G 1

Chain	Residue
G	PHE36
G	TYR39
G	GLN45
G	MET48
G	ARG54
G	GLY78
G	THR79
G	GLU100
G	ALA101
G	GLY126
G	SER127
G	VAL128
G	GLU129
G	GLU143
G	MET154
G	SER157
G	HOH391
G	HOH400

---

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAH A 1

Chain	Residue
A	TYR39
A	GLN45
A	ARG54
A	GLY78
A	THR79
A	ILE83
A	LEU84
A	VAL99
A	GLU100
A	ALA101
A	GLY126
A	SER127
A	VAL128
A	GLU129
A	GLU143
A	MET154
A	SER157
A	HOH414

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE SAH E 1

Chain	Residue
E	TYR35
E	PHE36
E	TYR39
E	GLN45
E	MET48
E	ARG54
E	GLY78
E	THR79
E	VAL99
E	GLU100
E	ALA101
E	GLY126
E	VAL128
E	GLU129
E	GLU143
E	MET154
E	SER157
E	HOH403
E	HOH407

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	160
Details	Region: {"description":"Dimerization arm"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	20
Details	Binding site: {}

Chain

Residue

Details

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