3R0O
Crystal structure of carnitinyl-CoA hydratase from Mycobacterium avium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006635 | biological_process | fatty acid beta-oxidation |
| A | 0016829 | molecular_function | lyase activity |
| A | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006635 | biological_process | fatty acid beta-oxidation |
| B | 0016829 | molecular_function | lyase activity |
| B | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006631 | biological_process | fatty acid metabolic process |
| C | 0006635 | biological_process | fatty acid beta-oxidation |
| C | 0016829 | molecular_function | lyase activity |
| C | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 270 |
| Chain | Residue |
| A | TYR97 |
| A | HIS100 |
| A | THR106 |
| A | ALA124 |
| A | HOH280 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 270 |
| Chain | Residue |
| B | HOH300 |
| B | TYR97 |
| B | HIS100 |
| B | THR106 |
| B | ALA124 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 270 |
| Chain | Residue |
| C | TYR97 |
| C | HIS100 |
| C | ILE102 |
| C | THR106 |
| C | ALA124 |
| C | HOH279 |
| C | HOH311 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 271 |
| Chain | Residue |
| B | ASN186 |
| B | GLU187 |
| B | ARG204 |
| B | HOH552 |
| C | GLU166 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 271 |
| Chain | Residue |
| A | ARG181 |
| A | TRP182 |
| B | ARG181 |
| C | ARG181 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 272 |
| Chain | Residue |
| B | PHE94 |
| B | GLY117 |
| B | GLU120 |
| B | GLU140 |
| B | ILE146 |
| B | GLY148 |
| B | ALA149 |
| B | PHE242 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K C 271 |
| Chain | Residue |
| C | GLU120 |
| C | GLU140 |
Functional Information from PROSITE/UniProt
| site_id | PS00166 |
| Number of Residues | 21 |
| Details | ENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. IAaVNGtalGGGselaLaSDL |
| Chain | Residue | Details |
| A | ILE107-LEU127 |
