3QZO

Staphylococcus aureus IsdA NEAT domain in complex with heme, reduced crystal

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM A 200

Chain	Residue
A	LYS75
A	TYR166
A	TYR170
A	THR172
A	HOH187
B	PRO162
B	GLN163
B	ILE164
B	ASN165
C	PRO162
C	GLN163
A	SER82
A	HIS83
A	MET84
A	TYR87
A	PHE112
A	TRP113
A	ILE159
A	ILE164

---

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM B 200

Chain	Residue
A	PRO162
A	GLN163
A	ASN165
B	LYS75
B	SER82
B	HIS83
B	MET84
B	TYR87
B	PHE112
B	TRP113
B	ILE159
B	TYR166
B	TYR170
B	THR172
B	HOH288

---

site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM C 200

Chain	Residue
C	LYS75
C	SER82
C	HIS83
C	MET84
C	TYR87
C	PHE112
C	TRP113
C	ILE159
C	VAL161
C	ILE164
C	TYR166
C	TYR170
C	THR172
C	HOH185
C	HOH195
C	HOH244
D	ASP86
D	TYR87
D	HEM200

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 2

Chain	Residue
C	LYS114
C	HIS158
C	ASN167
C	ARG169
C	HOH369

---

site_id	AC5
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM D 200

Chain	Residue
C	ASP86
C	TYR87
C	HOH197
C	HEM200
C	HOH213
D	HOH4
D	HOH15
D	LYS75
D	SER82
D	HIS83
D	MET84
D	TYR87
D	TRP113
D	ILE159
D	VAL161
D	ILE164
D	TYR166
D	TYR170
D	THR172
D	HOH185
D	HOH212

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL D 1

Chain	Residue
D	LYS114
D	HIS158
D	ASN167

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"21893067","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	244
Details	Domain: {"description":"NEAT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00337","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---