3QW2
L-myo-inositol 1-phosphate synthase from Archaeoglobus mutant N255A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004512 | molecular_function | inositol-3-phosphate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006021 | biological_process | inositol biosynthetic process |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008654 | biological_process | phospholipid biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004512 | molecular_function | inositol-3-phosphate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006021 | biological_process | inositol biosynthetic process |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008654 | biological_process | phospholipid biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004512 | molecular_function | inositol-3-phosphate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006021 | biological_process | inositol biosynthetic process |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0008654 | biological_process | phospholipid biosynthetic process |
| C | 0016020 | cellular_component | membrane |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004512 | molecular_function | inositol-3-phosphate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006021 | biological_process | inositol biosynthetic process |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0008654 | biological_process | phospholipid biosynthetic process |
| D | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 395 |
| Chain | Residue |
| A | LYS227 |
| A | THR228 |
| A | GLY229 |
| A | GLU230 |
| A | THR231 |
| A | LYS306 |
| A | LYS367 |
| A | GOL397 |
| A | HOH440 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD A 396 |
| Chain | Residue |
| A | GLY7 |
| A | GLY10 |
| A | ILE11 |
| A | VAL12 |
| A | HIS56 |
| A | GLU57 |
| A | ILE58 |
| A | ARG59 |
| A | THR99 |
| A | VAL147 |
| A | ALA148 |
| A | SER149 |
| A | THR150 |
| A | ALA181 |
| A | TYR185 |
| A | PHE199 |
| A | THR200 |
| A | PRO201 |
| A | ASP225 |
| A | GLY226 |
| A | THR228 |
| A | TYR260 |
| A | ASP261 |
| A | ASP332 |
| A | ALA336 |
| A | GOL397 |
| A | HOH409 |
| A | HOH453 |
| A | HOH462 |
| A | HOH487 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 397 |
| Chain | Residue |
| A | ASP261 |
| A | LEU265 |
| A | LYS274 |
| A | ILE296 |
| A | LYS306 |
| A | ASP332 |
| A | PO4395 |
| A | NAD396 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 393 |
| Chain | Residue |
| A | ASP371 |
| A | THR372 |
| A | ASN373 |
| A | VAL374 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K A 394 |
| Chain | Residue |
| A | ASP329 |
| B | TYR325 |
| C | TYR325 |
| D | ASP329 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 395 |
| Chain | Residue |
| B | LYS227 |
| B | THR228 |
| B | GLY229 |
| B | GLU230 |
| B | THR231 |
| B | LYS306 |
| B | LYS367 |
| site_id | AC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAD B 396 |
| Chain | Residue |
| B | VAL6 |
| B | GLY7 |
| B | GLY10 |
| B | ILE11 |
| B | VAL12 |
| B | GLU57 |
| B | ILE58 |
| B | ARG59 |
| B | THR99 |
| B | VAL147 |
| B | ALA148 |
| B | SER149 |
| B | THR150 |
| B | ALA181 |
| B | TYR185 |
| B | PHE199 |
| B | THR200 |
| B | PRO201 |
| B | ASP225 |
| B | GLY226 |
| B | THR228 |
| B | TYR260 |
| B | ASP261 |
| B | ASP332 |
| B | ALA336 |
| B | GOL397 |
| B | HOH435 |
| B | HOH445 |
| B | HOH479 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 397 |
| Chain | Residue |
| B | ASP261 |
| B | LEU265 |
| B | LYS274 |
| B | ILE296 |
| B | LYS306 |
| B | ASP332 |
| B | LYS367 |
| B | NAD396 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 393 |
| Chain | Residue |
| B | LYS211 |
| B | MET370 |
| B | ASP371 |
| B | HOH476 |
| B | HOH493 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 394 |
| Chain | Residue |
| B | LYS360 |
| B | THR372 |
| B | ASN373 |
| B | VAL374 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 395 |
| Chain | Residue |
| C | LYS227 |
| C | THR228 |
| C | GLY229 |
| C | GLU230 |
| C | THR231 |
| C | LYS306 |
| C | LYS367 |
| C | HOH470 |
| site_id | BC3 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAD C 396 |
| Chain | Residue |
| C | GLY7 |
| C | TYR9 |
| C | GLY10 |
| C | ILE11 |
| C | VAL12 |
| C | HIS56 |
| C | GLU57 |
| C | ILE58 |
| C | ARG59 |
| C | THR99 |
| C | LEU110 |
| C | VAL147 |
| C | ALA148 |
| C | SER149 |
| C | THR150 |
| C | TYR185 |
| C | PHE199 |
| C | THR200 |
| C | PRO201 |
| C | ASP225 |
| C | GLY226 |
| C | THR228 |
| C | TYR260 |
| C | ASP261 |
| C | ASP332 |
| C | ALA336 |
| C | K398 |
| C | HOH408 |
| C | HOH409 |
| C | HOH456 |
| C | HOH469 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 393 |
| Chain | Residue |
| C | ARG96 |
| C | LYS97 |
| C | ARG129 |
| D | LYS87 |
| D | SER88 |
| D | GLU91 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 394 |
| Chain | Residue |
| B | TRP72 |
| B | ARG80 |
| C | TRP72 |
| C | ARG76 |
| C | ARG80 |
| C | HOH514 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 397 |
| Chain | Residue |
| C | LYS360 |
| C | THR372 |
| C | ASN373 |
| C | VAL374 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K C 398 |
| Chain | Residue |
| C | ASP304 |
| C | NAD396 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 D 395 |
| Chain | Residue |
| D | GLY226 |
| D | THR228 |
| D | GLY229 |
| D | GLU230 |
| D | THR231 |
| D | LYS306 |
| D | LYS367 |
| D | HOH524 |
| site_id | BC9 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE NAD D 396 |
| Chain | Residue |
| D | GLY7 |
| D | GLY10 |
| D | ILE11 |
| D | VAL12 |
| D | GLU57 |
| D | ARG59 |
| D | HIS71 |
| D | THR99 |
| D | ALA100 |
| D | CYS103 |
| D | LEU110 |
| D | VAL147 |
| D | ALA148 |
| D | SER149 |
| D | THR150 |
| D | ALA181 |
| D | TYR185 |
| D | PHE199 |
| D | THR200 |
| D | PRO201 |
| D | ASP225 |
| D | GLY226 |
| D | THR228 |
| D | TYR260 |
| D | ASP261 |
| D | ASP332 |
| D | ALA336 |
| D | LYS367 |
| D | K397 |
| D | HOH398 |
| D | HOH412 |
| D | HOH447 |
| D | HOH524 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 393 |
| Chain | Residue |
| D | LYS360 |
| D | THR372 |
| D | ASN373 |
| D | VAL374 |
| D | HOH530 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 394 |
| Chain | Residue |
| D | SER157 |
| D | GLU158 |
| D | GLU159 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K D 397 |
| Chain | Residue |
| D | ILE11 |
| D | ASP304 |
| D | ASP332 |
| D | NAD396 |
