3QVW

L-myo-inositol 1-phosphate synthase from Archaeoglobus fulgidus mutant K278A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004512	molecular_function	inositol-3-phosphate synthase activity
A	0006021	biological_process	inositol biosynthetic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0016020	cellular_component	membrane
A	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 A 395

Chain	Residue
A	LYS360
A	THR372
A	ASN373
A	VAL374

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site_id	AC2
Number of Residues	33
Details	BINDING SITE FOR RESIDUE NAD A 396

Chain	Residue
A	GLU57
A	ARG59
A	THR99
A	CYS103
A	ILE107
A	VAL147
A	ALA148
A	SER149
A	THR150
A	TYR185
A	PHE199
A	THR200
A	ASP225
A	GLY226
A	THR228
A	TYR260
A	ASP261
A	LYS274
A	ASP332
A	ALA336
A	GOL397
A	HOH414
A	HOH417
A	HOH420
A	HOH427
A	HOH432
A	HOH436
A	HOH496
A	GLY7
A	TYR9
A	GLY10
A	ILE11
A	VAL12

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PG4 A 399

Chain	Residue
A	GLU131
A	GLU132
A	LYS135
A	SER289
A	PRO290
A	TYR291
A	SER292

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 A 520

Chain	Residue
A	THR228
A	GLY229
A	GLU230
A	THR231
A	LYS306
A	LYS367
A	GOL397
A	HOH440
A	HOH493

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 521

Chain	Residue
A	ASN75
A	SER301
A	LEU302
A	ASN305
A	LYS323
A	ILE331

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site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 397

Chain	Residue
A	ASP261
A	LYS274
A	LYS306
A	ASP332
A	LYS367
A	NAD396
A	PO4520

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 398

Chain	Residue
A	LYS217
A	LYS263
A	TYR298
A	HOH583

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 525

Chain	Residue
A	TYR325
A	TYR325
A	ASP329
A	ASP329

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