3QVT

L-myo-inositol 1-phosphate synthase from Archaeoglobus fulgidus wild-type with the intermediate 5-keto 1-phospho glucose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004512	molecular_function	inositol-3-phosphate synthase activity
A	0005737	cellular_component	cytoplasm
A	0006021	biological_process	inositol biosynthetic process
A	0006629	biological_process	lipid metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 A 395

Chain	Residue
A	LYS360
A	THR372
A	ASN373

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site_id	AC2
Number of Residues	32
Details	BINDING SITE FOR RESIDUE NAI A 396

Chain	Residue
A	ARG59
A	THR99
A	ALA100
A	CYS103
A	VAL147
A	ALA148
A	SER149
A	THR150
A	TYR185
A	PHE199
A	ASP225
A	GLY226
A	THR228
A	TYR260
A	ASP261
A	LYS274
A	ASP332
A	LYS367
A	HOH412
A	HOH415
A	HOH418
A	HOH430
A	HOH434
A	HOH494
A	PO4519
A	KPG520
A	GLY7
A	TYR9
A	GLY10
A	ILE11
A	VAL12
A	GLU57

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PG4 A 399

Chain	Residue
A	GLU131
A	GLU132
A	LYS135
A	SER289
A	PRO290
A	TYR291
A	SER292

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 A 519

Chain	Residue
A	THR228
A	GLY229
A	GLU230
A	THR231
A	LYS278
A	LYS306
A	LYS367
A	NAI396
A	HOH438

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE KPG A 520

Chain	Residue
A	THR228
A	GLY229
A	GLU230
A	THR231
A	LEU232
A	ASN255
A	LEU257
A	ASP261
A	LEU265
A	LYS274
A	LYS278
A	ILE296
A	LYS306
A	ASP332
A	LYS367
A	HOH393
A	NAI396
A	HOH438

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site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 521

Chain	Residue
A	ASN305
A	LYS320
A	LEU321
A	MET322
A	LYS323
A	ASP329
A	ILE331
A	HOH584
A	HOH584
A	HOH603
A	HOH609

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 525

Chain	Residue
A	TYR325
A	TYR325
A	ASP329
A	ASP329

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