3QVF
Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with MgADP and fosfomycin vanadate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004349 | molecular_function | glutamate 5-kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006561 | biological_process | proline biosynthetic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0102043 | molecular_function | isopentenyl phosphate kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ADP A 1260 |
| Chain | Residue |
| A | LYS9 |
| A | ILE175 |
| A | VAL176 |
| A | ALA200 |
| A | LEU201 |
| A | TRP202 |
| A | ASP208 |
| A | ALA212 |
| A | MET213 |
| A | LYS216 |
| A | HOH279 |
| A | GLY11 |
| A | HOH298 |
| A | HOH330 |
| A | HOH350 |
| A | HOH357 |
| A | HOH375 |
| A | FV14001 |
| A | MG5000 |
| A | GLY12 |
| A | SER13 |
| A | LYS18 |
| A | THR170 |
| A | ASP171 |
| A | VAL172 |
| A | GLY174 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FV1 A 4001 |
| Chain | Residue |
| A | LYS9 |
| A | GLY11 |
| A | GLY12 |
| A | LYS18 |
| A | GLY52 |
| A | GLY53 |
| A | GLY54 |
| A | GLY57 |
| A | HIS58 |
| A | PHE147 |
| A | SER148 |
| A | SER149 |
| A | ASP208 |
| A | THR210 |
| A | HOH287 |
| A | HOH357 |
| A | HOH375 |
| A | ADP1260 |
| A | MG5000 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 5000 |
| Chain | Residue |
| A | ASP150 |
| A | HOH330 |
| A | HOH357 |
| A | HOH375 |
| A | ADP1260 |
| A | FV14001 |
