3QV2
Structure Analysis of Entamoeba histolytica methyltransferase EhMeth
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003886 | molecular_function | DNA (cytosine-5-)-methyltransferase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0010526 | biological_process | transposable element silencing |
| A | 0010628 | biological_process | positive regulation of gene expression |
| A | 0010629 | biological_process | negative regulation of gene expression |
| A | 0016427 | molecular_function | tRNA (cytidine) methyltransferase activity |
| A | 0016428 | molecular_function | tRNA (cytidine-5-)-methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0032259 | biological_process | methylation |
| A | 0040029 | biological_process | epigenetic regulation of gene expression |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SAH A 323 |
| Chain | Residue |
| A | PHE12 |
| A | LEU59 |
| A | ASP60 |
| A | SER78 |
| A | PRO80 |
| A | HOH396 |
| A | HOH440 |
| A | SER13 |
| A | GLY14 |
| A | ILE15 |
| A | GLY17 |
| A | ASP37 |
| A | ILE38 |
| A | ASN39 |
| A | ASN58 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 324 |
| Chain | Residue |
| A | LYS57 |
| A | GLN146 |
| A | HOH373 |
| A | HOH375 |
| A | HOH491 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 325 |
| Chain | Residue |
| A | LYS4 |
| A | ASN73 |
| A | LYS119 |
| A | HOH433 |
| A | HOH468 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 326 |
| Chain | Residue |
| A | ASN272 |
| A | LYS276 |
| A | HOH407 |
