3QUR
Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with MgADP and fosfomycin monophosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004349 | molecular_function | glutamate 5-kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0102043 | molecular_function | isopentenyl phosphate kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE ADP A 1260 |
| Chain | Residue |
| A | LYS9 |
| A | VAL176 |
| A | ALA200 |
| A | LEU201 |
| A | SER204 |
| A | SER205 |
| A | ALA212 |
| A | MET213 |
| A | LYS216 |
| A | HOH281 |
| A | HOH286 |
| A | GLY11 |
| A | HOH319 |
| A | HOH416 |
| A | HOH438 |
| A | HOH470 |
| A | FM42000 |
| A | MG3000 |
| A | GLY12 |
| A | SER13 |
| A | THR170 |
| A | ASP171 |
| A | VAL172 |
| A | GLY174 |
| A | ILE175 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE FM4 A 2000 |
| Chain | Residue |
| A | LYS9 |
| A | GLY11 |
| A | GLY12 |
| A | GLY52 |
| A | GLY53 |
| A | PHE147 |
| A | SER148 |
| A | SER149 |
| A | HOH305 |
| A | HOH350 |
| A | HOH435 |
| A | HOH470 |
| A | ADP1260 |
| A | MG3000 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 3000 |
| Chain | Residue |
| A | ASP150 |
| A | ALA212 |
| A | LYS216 |
| A | HOH435 |
| A | ADP1260 |
| A | FM42000 |
