3QSV
Structural basis for DNA recognition by constitutive Smad4 MH1 dimers
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005667 | cellular_component | transcription regulator complex |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0005667 | cellular_component | transcription regulator complex |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0005667 | cellular_component | transcription regulator complex |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0005667 | cellular_component | transcription regulator complex |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | CYS71 |
| A | CYS115 |
| A | CYS127 |
| A | HIS132 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2 |
| Chain | Residue |
| B | CYS71 |
| B | CYS115 |
| B | CYS127 |
| B | HIS132 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 3 |
| Chain | Residue |
| C | CYS115 |
| C | CYS127 |
| C | HIS132 |
| C | CYS71 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 4 |
| Chain | Residue |
| D | CYS71 |
| D | CYS115 |
| D | CYS127 |
| D | HIS132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 100 |
| Details | Region: {"description":"Required for interaction with TSC22D1","evidences":[{"source":"UniProtKB","id":"Q13485","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q13485","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"UniProtKB","id":"Q13485","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
